List of works - Andres Metspalu

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Population genetic differentiation of height and body mass index across Europe

scientific article

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

scientific article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

scientific article published on 12 May 2013

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

scientific article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

scientific article

A metabolic view on menopause and ageing

scientific article published on 21 August 2014

Copy number variations and cognitive phenotypes in unselected populations

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

scientific article published on February 2017

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

scientific article published on 5 May 2015

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

A variant in MCF2L is associated with osteoarthritis

scientific article

Global implementation of genomic medicine: We are not alone

scientific article

Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL

scientific journal article

Dominance genetic variation contributes little to the missing heritability for human complex traits

scientific article

Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project

scientific article

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

scientific article

Toward a roadmap in global biobanking for health

scientific article (publication date: November 2012)

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities

scientific article published on 2 December 2015

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

scientific article published on 19 August 2015

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

scientific article

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population

scientific article

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

scientific article

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity

scientific article

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers

scientific article

A meta-analysis of gene expression signatures of blood pressure and hypertension

scientific article (publication date: March 2015)

Evidence of inbreeding depression on human height

scientific article

Chronotype and sleep duration: the influence of season of assessment

scientific article published on 28 March 2014

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Signatures of negative selection in the genetic architecture of human complex traits

scientific article published on 16 April 2018

Comprehensive catalog of European biobanks

scientific article published on 8 September 2011

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

scientific article

Replication and meta-analysis of TMEM132D gene variants in panic disorder

scientific article published on 4 September 2012

Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function

scientific article published on 19 August 2013

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

scientific article published on 29 March 2016

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

scientific article published on 03 October 2016

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

scientific article

Structure and expression of the genes coding for human alpha 1-acid glycoprotein

scientific article

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Association study of 90 candidate gene polymorphisms in panic disorder

scientific article

List of works by Andres Metspalu

Directional dominance on stature and cognition in diverse human populations

Population genetic differentiation of height and body mass index across Europe

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

A metabolic view on menopause and ageing

Copy number variations and cognitive phenotypes in unselected populations

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

A variant in MCF2L is associated with osteoarthritis

Global implementation of genomic medicine: We are not alone

Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL

Dominance genetic variation contributes little to the missing heritability for human complex traits

Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

Toward a roadmap in global biobanking for health

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers

A meta-analysis of gene expression signatures of blood pressure and hypertension

Evidence of inbreeding depression on human height

Chronotype and sleep duration: the influence of season of assessment

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Cell Specific eQTL Analysis without Sorting Cells

Signatures of negative selection in the genetic architecture of human complex traits

Comprehensive catalog of European biobanks

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Replication and meta-analysis of TMEM132D gene variants in panic disorder

Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

Structure and expression of the genes coding for human alpha 1-acid glycoprotein

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

Association study of 90 candidate gene polymorphisms in panic disorder