List of works - Andres Metspalu

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Genetics of rheumatoid arthritis contributes to biology and drug discovery

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

scientific article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

A first-generation linkage disequilibrium map of human chromosome 22

scientific article published in Nature

Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes

scientific article

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

scientific article

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

scientific article published on July 3, 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

High carrier frequency of the 35delG deafness mutation in European populations

article published in 2000

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

List of works by Andres Metspalu

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Genetic studies of body mass index yield new insights for obesity biology

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Systematic identification of trans eQTLs as putative drivers of known disease associations

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Defining the role of common variation in the genomic and biological architecture of adult human height

Large-scale association analysis identifies new risk loci for coronary artery disease

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

New genetic loci link adipose and insulin biology to body fat distribution

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Genome-wide association study identifies 74 loci associated with educational attainment

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

Identification of seven loci affecting mean telomere length and their association with disease

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

The genetic architecture of type 2 diabetes

Common variants associated with plasma triglycerides and risk for coronary artery disease

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Common variants in KCNN3 are associated with lone atrial fibrillation

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Analysis of shared heritability in common disorders of the brain

New gene functions in megakaryopoiesis and platelet formation

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

FTO genotype is associated with phenotypic variability of body mass index

A first-generation linkage disequilibrium map of human chromosome 22

Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Seventy-five genetic loci influencing the human red blood cell

Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

Rare and low-frequency coding variants alter human adult height

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

High carrier frequency of the 35delG deafness mutation in European populations

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci