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List of works by Carl R Walkley

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Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

scientific article published on June 2007
A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency

scientific article
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment

scientific article published on June 2007
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

scientific article
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

scientific article published on 14 November 2011
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

scientific article
Dynamic landscape and regulation of RNA editing in mammals.

scientific article published in October 2017
RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation

scientific article
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

scientific article published on 29 July 2004
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

scientific article
Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells

scientific article published on 16 January 2005
Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment

scientific article published on 18 March 2011
Cells of origin in osteosarcoma: mesenchymal stem cells or osteoblast committed cells?

scientific article published on 14 February 2014
Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies.

scientific article
BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

scientific article published on 6 May 2015
Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation

scientific article published on April 2015
Generation and analysis of Siah2 mutant mice.

scientific article
Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells

scholarly article
MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity

scientific article
Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs

scientific article published on 30 October 2017
Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

scientific article published on 26 February 2013
Retinoic acid receptor antagonism in vivo expands the numbers of precursor cells during granulopoiesis.

scientific article published on September 2002
The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.

scientific article
Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation

scientific article
Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

scientific article published on 10 April 2015
ADAR1, inosine and the immune sensing system: distinguishing self from non-self

scientific article
Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

scientific article published on 04 April 2016
Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo

scientific article published on 21 July 2014
Identification of the molecular requirements for an RAR alpha-mediated cell cycle arrest during granulocytic differentiation.

scientific article published on 23 October 2003
Genetically engineered mouse models and human osteosarcoma

scientific article
HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

scientific article published on 12 January 2015
Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion

scientific article published on 8 December 2011
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

scientific article published on 5 September 2017
Rb and hematopoiesis: stem cells to anemia

scientific article published on 8 September 2008
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

scientific article published on 4 April 2016
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

scientific article
mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation

scientific article published on 9 January 2017
The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma

scientific article published on 27 January 2016
Erythropoiesis, anemia and the bone marrow microenvironment.

scientific article published on 12 January 2011
Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.

scientific article published on 30 June 2016
The DNA helicase recql4 is required for normal osteoblast expansion and osteosarcoma formation

scientific article
Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

scientific article published on 12 April 2016
RARγ is a negative regulator of osteoclastogenesis

scientific article published on 20 March 2015
The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

scientific article
Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

scientific article
The role of RNA editing by ADAR1 in prevention of innate immune sensing of self-RNA.

scientific article published on 5 April 2016
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.

scientific article published on 10 January 2014
Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma

scientific article published on 5 January 2015
Src family kinases and their role in hematological malignancies

scientific article
Adar3 Is Involved in Learning and Memory in Mice

scientific article

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