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List of works by Nicole Borth

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Recon 2.2: from reconstruction to model of human metabolism

scientific article
Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

scientific article published in February 2004
Chinese hamster genome sequenced from sorted chromosomes

scientific article published in August 2013
Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

scientific article
Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors

scientific article published on August 2006
Applications of cell sorting in biotechnology

scientific article
Genetically different wine yeasts isolated from Austrian vine-growing regions influence wine aroma differently and contain putative hybrids betweenSaccharomyces cerevisiaeandSaccharomyces kudriavzevii

scientific article published on 30 April 2007
Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon

scientific article published on 2 November 2010
Baculovirus surface display: Construction and screening of a eukaryotic epitope library

scientific article published on April 1, 1998
Improvement of lactic acid production in Saccharomyces cerevisiae by cell sorting for high intracellular pH.

scientific article published on August 2006
Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

scientific article
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing

scientific article
Intracellular pH distribution in Saccharomyces cerevisiae cell populations, analyzed by flow cytometry

scientific article published on March 2005
Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org

scientific article
CHO microRNA engineering is growing up: recent successes and future challenges

scientific article published on 02 August 2013
Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

scientific article
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.

scientific article published on 12 April 2016
Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures

scientific article published on 5 August 2011
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

scientific article published on November 2016
Modulation of neural carbohydrate epitope expression in Drosophila melanogaster cells

scientific article published on 28 November 2005
Changes during subclone development and ageing of human antibody-producing recombinant CHO cells

scientific article published on April 1999
Process parameter shifting: Part II. Biphasic cultivation-A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells

scientific article published in August 2006
Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry

scientific article published in May 2003
Selection of CHO host cell subclones with increased specific antibody production rates by repeated cycles of transient transfection and cell sorting

scientific article published on February 2011
Reducing Recon 2 for steady-state flux analysis of HEK cell culture

article
miRNAs – pathway engineering of CHO cell factories that avoids translational burdening

scientific article published on June 4, 2012
Efficient selection of high-producing subclones during gene amplification of recombinant Chinese hamster ovary cells by flow cytometry and cell sorting

scientific article published on January 2000
A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells

scientific article
Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics

scientific article published on 2 March 2012
Immunoglobulin G specifically binding plant N-glycans with high affinity could be generated in rabbits but not in mice

scientific article
Stable overexpression of miR-17 enhances recombinant protein production of CHO cells

scientific article published on 8 February 2014
Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines

scientific article published on 10 January 2014
Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth

scientific article published on 9 December 2011
Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

scientific article published on 25 January 2012
CHO-K1 host cells adapted to growth in glutamine-free medium by FACS-assisted evolution

scientific article published on October 2010
Optimization of sorting conditions for the selection of stable, high-producing mammalian cell lines

scientific article published on September 1999
Determination of liposome size distribution by flow cytometry

scientific article
A study on the temperature dependency and time course of the cold capture antibody secretion assay

scientific article
Analysis of changes during subclone development and ageing of human antibody-producing heterohybridoma cells by northern blot and flow cytometry.

scientific article published on January 1999
Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing

scientific article published on August 2011
Growth and production kinetics of human x mouse and mouse hybridoma cells at reduced temperature and serum content

scientific article published on September 1992
Flow-cytometry and cell sorting: an efficient approach to investigate productivity and cell physiology in mammalian cell factories

scientific article published on 14 March 2012
High-throughput screening and selection of mammalian cells for enhanced protein production

scientific article published on 8 June 2016
Prediction of transcribed PIWI-interacting RNAs from CHO RNAseq data

scientific article
Nuclear flow FISH: isolation of cell nuclei improves the determination of telomere lengths

scientific article
Improvement of the energy metabolism of recombinant CHO cells by cell sorting for reduced mitochondrial membrane potential

scientific article published on 14 February 2007
Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

scientific article published on 21 July 2016
Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells

scientific article published on 12 February 2014
Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

scientific article
Comparison of the production of a human monoclonal antibody against HIV-1 by heterohybridoma cells and recombinant CHO cells: A flow cytometric study

scientific article

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