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List of works by William E. Klunk

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The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

scientific article (publication date: May 2011)
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

scientific article (publication date: 21 January 2004)
Clinical and biomarker changes in dominantly inherited Alzheimer's disease

scientific article
Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

scientific article (publication date: 24 August 2005)
Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

scientific article published on January 23, 2014
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans

scientific article published in March 2006
[11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease

scientific article published on 01 August 2006
Frequent amyloid deposition without significant cognitive impairment among the elderly

scientific article
Imaging beta-amyloid burden in aging and dementia.

scientific article
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

scientific article
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

scientific article
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

scholarly article
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

scientific article
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease

scientific article published on 10 October 2007
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

scientific article published on 26 February 2010
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B.

scientific article
Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents

scientific article
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy

scientific article published in September 2007
Amyloid imaging in mild cognitive impairment subtypes.

scientific article
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees

scientific article published on June 2007
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance

scientific article published on April 2008
Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report

scientific article published on March 2007
Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab

scientific article published on 10 October 2011
11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration

scientific article
Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

scientific article
Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.

scientific article
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

scientific article published in May 2015
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

scientific article
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain

scientific article
Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid

scientific article published on 06 March 2009
Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve.

scientific article
Brain imaging in Alzheimer disease

scientific article
Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia

scientific article published on 21 June 2011
Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology

scientific article published on 03 July 2013
Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report

scientific article published on December 2009
Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

scientific article (publication date: October 2012)
Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay

scientific article
Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice

scientific article
The role of biomarkers in clinical trials for Alzheimer disease

scientific article
In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers

scientific article
Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease.

scientific article published in January 2003
Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease

scientific article published on 21 September 2007
Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.

scientific article published on January 2009
Early detection of Alzheimer's disease using PiB and FDG PET

scientific article
Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

scientific article
Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults.

scientific article
Imaging of CNS myelin by positron-emission tomography

scholarly article
Partial volume correction in quantitative amyloid imaging

scientific article published on 5 December 2014
Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury

scientific article

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