List of works - Dietmar Vestweber

Functionally specialized junctions between endothelial cells of lymphatic vessels

scientific article

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

scientific article published in Nature

VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

scientific article published on 27 December 2007

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo

scientific article

Cadherin interaction probed by atomic force microscopy

scholarly article

Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells

scientific article published on January 1985

Junctional adhesion molecules (JAMs): more molecules with dual functions?

scientific article published on January 2004

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

scientific article

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

scientific article published on 24 April 2011

How leukocytes cross the vascular endothelium

scientific article published on October 16, 2015

The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

scientific article

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

scientific article

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1

scientific article published on October 1, 1993

The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

scientific article published in September 2012

Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1

scientific article

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

scientific article

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

scientific article

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter

scientific article

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin

scientific article published on 09 February 2014

Adhesion and signaling molecules controlling the transmigration of leukocytes through endothelium

scientific article published on August 2007

Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44

scientific article

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

scientific article (publication date: October 2003)

Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player

scientific article

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

scientific article

A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein.

scientific article

Spatial regulation of VEGF receptor endocytosis in angiogenesis

scientific journal article

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

scientific article

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

scientific article

P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo

scientific article

Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration

scientific article published on January 2008

P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin

scientific article published on February 1997

P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli

scientific article

Identification of a putative cell adhesion domain of uvomorulin.

scientific article published on December 1985

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

scientific article

VE-cadherin antibody accelerates neutrophil recruitment in vivo

scientific article published on 01 March 1997

Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins

scientific article published on 01 December 1989

A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites

scientific article

Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development

scientific article

ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability

scientific article

Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain

scientific article published on 26 April 2009

Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1

scientific article

A transmembrane tight junction protein selectively expressed on endothelial cells and platelets

scientific article (publication date: 3 May 2002)

The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin

scientific article published on December 1998

Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors

scientific article published on 01 February 2002

The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion

scientific article published on 01 December 1987

Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines.

scientific article

Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos

scientific article published on 01 December 1987

Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-alpha in vivo

scientific article

Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.

scientific article

Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis

scholarly article

List of works by Dietmar Vestweber

Functionally specialized junctions between endothelial cells of lymphatic vessels

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo

Cadherin interaction probed by atomic force microscopy

Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells

Junctional adhesion molecules (JAMs): more molecules with dual functions?

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

How leukocytes cross the vascular endothelium

The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1

The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin

Adhesion and signaling molecules controlling the transmigration of leukocytes through endothelium

Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein.

Spatial regulation of VEGF receptor endocytosis in angiogenesis

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo

Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration

P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin

P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli

Identification of a putative cell adhesion domain of uvomorulin.

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

VE-cadherin antibody accelerates neutrophil recruitment in vivo

Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins

A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites

Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development

ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability

Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain

Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1

A transmembrane tight junction protein selectively expressed on endothelial cells and platelets

The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin

Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors

The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion

Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines.

Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos

Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-alpha in vivo

Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.

Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis