List of works - Dean Nižetić

The DNA sequence of human chromosome 21

scientific article (publication date: 18 May 2000)

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

scientific article

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

scientific article

High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe.

scientific article published on April 1993

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

scientific article (publication date: September 2015)

Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function

scientific article (publication date: June 2001)

Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries

scientific article

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

scientific article

Evolutionary relationships between the t and H-2 haplotypes in the house mouse

scientific article published on January 1, 1984

Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries

scientific article published on August 1, 1995

Tumorigenesis in Down's syndrome: big lessons from a small chromosome

scientific article published on September 21, 2012

Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome

scientific article

Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical Alzheimer's disease?

scientific article published on 13 August 2015

Major histocompatibility complex gene organization in the mole rat Spalax ehrenbergi: evidence for transfer of function between class II genes

scientific article published on 01 August 1987

Chromosomal assignment of human YAC clones by fluorescence in situ hybridization: use of single-yeast-colony PCR and multiple labeling

scientific article

Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle

scientific article

Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome

scientific article

Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products

scientific article

Identification and characterization of a new human cDNA from chromosome 21q22.3 encoding a basic nuclear protein

scientific article

Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex

scientific article

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

scientific article

A high-resolution physical map of human chromosome 21p using yeast artificial chromosomes

scientific article

Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome

scientific article

High-Resolution YAC Fragmentation Map of 1q21

scientific article published on April 15, 1998

Rieger syndrome locus: a new reciprocal translocation t(4;12)(q25;q15) and a deletion del(4)(q25q27) both break between markers D4S2945 and D4S193

scientific article

Selection of a human chromosome 21 enriched YAC sub-library using a chromosome-specific composite probe

scientific article

Two sequence-ready contigs spanning the two copies of a 200-kb duplication on human 21q: partial sequence and polymorphisms

scientific article

Localisation of receptor interacting protein 140 (RIP140) within 100 kb of D21S13 on 21q11, a gene-poor region of the human genome

scientific article

High resolution physical mapping and identification of transcribed sequences in the Down syndrome region-2.

scientific article

High-resolution physical map and identification of potentially regulatory sequences of the human SH3BGR located in the Down syndrome chromosomal region

scientific article

Cytogenetic and molecular study of 32 Down syndrome families: potential leukaemia predisposing role of the most proximal segment of chromosome 21q

scientific article published on 01 October 1998

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP

scientific article published on January 1, 2015

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

scientific article published on 10 July 2020

Functional genomics of the Down syndrome

scientific article

Cerebral organoids with chromosome 21 trisomy secrete Alzheimer’s disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy

scientific article published on 15 December 2023

RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia

scientific article published on 27 November 2020

List of works by Dean Nižetić

The DNA sequence of human chromosome 21

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe.

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function

Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

Evolutionary relationships between the t and H-2 haplotypes in the house mouse

Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries

Tumorigenesis in Down's syndrome: big lessons from a small chromosome

Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome

Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical Alzheimer's disease?

Major histocompatibility complex gene organization in the mole rat Spalax ehrenbergi: evidence for transfer of function between class II genes

Chromosomal assignment of human YAC clones by fluorescence in situ hybridization: use of single-yeast-colony PCR and multiple labeling

Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle

Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome

Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products

Identification and characterization of a new human cDNA from chromosome 21q22.3 encoding a basic nuclear protein

Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

A high-resolution physical map of human chromosome 21p using yeast artificial chromosomes

Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome

High-Resolution YAC Fragmentation Map of 1q21

Rieger syndrome locus: a new reciprocal translocation t(4;12)(q25;q15) and a deletion del(4)(q25q27) both break between markers D4S2945 and D4S193

Selection of a human chromosome 21 enriched YAC sub-library using a chromosome-specific composite probe

Two sequence-ready contigs spanning the two copies of a 200-kb duplication on human 21q: partial sequence and polymorphisms

Localisation of receptor interacting protein 140 (RIP140) within 100 kb of D21S13 on 21q11, a gene-poor region of the human genome

High resolution physical mapping and identification of transcribed sequences in the Down syndrome region-2.

High-resolution physical map and identification of potentially regulatory sequences of the human SH3BGR located in the Down syndrome chromosomal region

Cytogenetic and molecular study of 32 Down syndrome families: potential leukaemia predisposing role of the most proximal segment of chromosome 21q

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Functional genomics of the Down syndrome

Cerebral organoids with chromosome 21 trisomy secrete Alzheimer’s disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy

RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia