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List of works by C R Leemans

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The molecular biology of head and neck cancer

scientific article published on 16 December 2010
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen

scientific article published in December 2007
A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications

scientific article published on April 15, 2003
The mutational landscape of adenoid cystic carcinoma

scientific article published on 19 May 2013
Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus

scientific article published in July 2004
Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments

scientific article
Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor

scientific article published on January 1994
Regional lymph node involvement and its significance in the development of distant metastases in head and neck carcinoma

scientific article published on January 1993
The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature

scientific article published on 01 November 2004
Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program

scientific article
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus

scientific article published on April 2006
The molecular landscape of head and neck cancer

scientific article published on 2 March 2018
Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions

scientific article
Phase 3 randomized trial on larynx preservation comparing sequential vs alternating chemotherapy and radiotherapy

scientific article published on 27 January 2009
A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus

scientific article
Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology

scientific article published in August 2008
Multiple head and neck tumors frequently originate from a single preneoplastic lesion

scientific article published on September 2002
Performance of immuno-positron emission tomography with zirconium-89-labeled chimeric monoclonal antibody U36 in the detection of lymph node metastases in head and neck cancer patients

scientific article
Increasing prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as assessed by a validated test algorithm.

scientific article published on 23 November 2012
Radiation dosimetry of 89Zr-labeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients

scientific article
(89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab.

scientific article published on November 2005
A genetic progression model of oral cancer: current evidence and clinical implications

scientific article
Screening for distant metastases in patients with head and neck cancer

scientific article published on March 2000
Human papillomavirus detection and comorbidity: critical issues in selection of patients with oropharyngeal cancer for treatment De-escalation trials

scientific article published on 14 August 2013
Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy

scientific article published on 08 August 2013
Oral and oropharyngeal cancer in The Netherlands between 1989 and 2006: Increasing incidence, but not in young adults

scientific article published on 19 May 2009
Distress in spouses and patients after treatment for head and neck cancer

scientific article published in February 2007
The efficacy of comprehensive neck dissection with or without postoperative radiotherapy in nodal metastases of squamous cell carcinoma of the upper respiratory and digestive tracts

scientific article published on November 1990
Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review

scientific article published on 26 June 2013
Incidence and survival trends of head and neck squamous cell carcinoma in the Netherlands between 1989 and 2011

scientific article published on 13 April 2014
Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications.

scientific article published on June 2001
Impact of radiation-induced xerostomia on quality of life after primary radiotherapy among patients with head and neck cancer

scientific article published on 8 June 2007
Mutated p53 as a molecular marker for the diagnosis of head and neck cancer

scientific article published on December 2002
Predictive modelling for swallowing dysfunction after primary (chemo)radiation: results of a prospective observational study.

scientific article
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study

scientific article published on June 2004
Elective and therapeutic selective neck dissection.

scientific article
A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer

scientific article published on 21 January 2009
Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30.

scientific article
Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities

scientific article published on 4 May 2002
Oral malignant melanoma: a review of the literature

scientific article published on 23 August 2006
Cordectomy by CO2 laser or radiotherapy for small T1a glottic carcinomas: costs, local control, survival, quality of life, and voice quality

scientific article published in February 2007
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients

scientific article
Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study

scientific article published on 01 June 2004
Molecular characterization of p16-immunopositive but HPV DNA-negative oropharyngeal carcinomas.

scientific article published on 19 November 2013
Employment and return to work in head and neck cancer survivors

scientific article published on 9 December 2009
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients

scientific article published on 11 November 2008
Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck.

scientific article
Changing concepts in the surgical management of the cervical node metastasis.

scientific article
Primary treatment of the anterior vocal commissure squamous carcinoma

scientific article published on 15 August 2006
Adenoid cystic carcinoma of the head and neck: a single-center analysis of 105 consecutive cases over a 30-year period.

scientific article published on 14 June 2013

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