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List of works by François Mach

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Genetic studies of body mass index yield new insights for obesity biology

scientific article
Discovery and refinement of loci associated with lipid levels

scientific article
New genetic loci link adipose and insulin biology to body fat distribution

scientific article
Rosuvastatin in older patients with systolic heart failure

scientific article
Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article
2016 European Guidelines on cardiovascular disease prevention in clinical practice

scientific article published on 27 June 2016
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016
Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis

scientific article
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors

scientific article published on 11 January 2017
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

scientific article published on 28 April 2016
Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability

CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke

Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways

article
The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.

scientific article
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction

scientific article published on 14 May 2012
Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke

scientific article
Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes

scientific article published on 4 July 2015
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article
Comparison of drug-eluting stents with bare metal stents in patients with ST-segment elevation myocardial infarction

scientific article published on 23 February 2012
Prognostic value of PCSK9 levels in patients with acute coronary syndromes

scientific article
Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice

scientific article published on 19 December 2012
Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

scientific article published on 06 February 2014
Profiling and validation of circulating microRNAs for cardiovascular events in patients presenting with ST-segment elevation myocardial infarction

scientific article published on 23 December 2016
Pathophysiology and Treatments of Oxidative Injury in Ischemic Stroke: Focus on the Phagocytic NADPH Oxidase 2

scientific article
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

scientific article published on 7 November 2013
Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability.

scientific article published on 24 November 2011
Serum levels of anti-apolipoprotein A-1 auto-antibodies and myeloperoxidase as predictors of major adverse cardiovascular events after carotid endarterectomy

scholarly article by Giovanni Spinella et al published 2013 in Thrombosis and Haemostasis
Reasons for discontinuation of recommended therapies according to the patients after acute coronary syndromes

scientific article
Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke

scientific article published on 24 April 2015
Safety profile of prasugrel and clopidogrel in patients with acute coronary syndromes in Switzerland

scientific article
Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness

scientific article published on 02 August 2007
Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

article published in 2015
Prognosis of Patients With Familial Hypercholesterolemia After Acute Coronary Syndromes

scientific article published on 26 July 2016
"In vivo" imaging of atherosclerosis.

scientific article published on 08 May 2012
Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.

scientific article
Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury

scientific article published on 4 April 2016
Effect of statins and non-statin LDL-lowering medications on cardiovascular outcomes in secondary prevention: a meta-analysis of randomized trials

scientific article published on 23 October 2017
Improved risk stratification of patients with acute coronary syndromes using a combination of hsTnT, NT-proBNP and hsCRP with the GRACE score

scientific article
Expected impact of applying new 2013 AHA/ACC cholesterol guidelines criteria on the recommended lipid target achievement after acute coronary syndromes

scientific article
Increased Proangiogenic Activity of Mobilized CD34+ Progenitor Cells of Patients With Acute ST-Segment-Elevation Myocardial Infarction: Role of Differential MicroRNA-378 Expression

scientific article published on 29 December 2016
Treatment with recombinant tissue plasminogen activator (r-TPA) induces neutrophil degranulation in vitro via defined pathways

scientific article published on 18 December 2014
Treatment with Evasin-3 abrogates neutrophil-mediated inflammation in mouse acute pancreatitis

scientific article
Inferior vena cava parameters predict re-admission in ischaemic heart failure

Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome

scientific article published on 9 January 2013
Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction

scientific article published on 6 January 2016
Quality of care after acute coronary syndromes in a prospective cohort with reasons for non-prescription of recommended medications

scientific article
Circulating FABP4 is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals

scientific article
Update on the role of neutrophils in atherosclerotic plaque vulnerability

scientific article
Potential pathophysiological role for the vitamin D deficiency in essential hypertension

scientific article
The role of adipocytokines in atherogenesis and atheroprogression

scientific article

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