List of works - Huixiao Hong

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

scientific article

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

scientific article

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

scientific article

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

scientific article published in July 2016

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

scientific article

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

scientific article

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

scientific article published on October 1, 2003

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

scientific article

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

scientific article

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

scientific article published on 25 June 2015

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

scientific article

Evaluation of external RNA controls for the assessment of microarray performance

scientific article published on September 2006

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

scientific article

Next-generation sequencing and its applications in molecular diagnostics

scientific article published on April 2011

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

scientific article

Development of public toxicogenomics software for microarray data management and analysis

scientific article

Toward Predictive Models for Drug-Induced Liver Injury in Humans: Are we There Yet?

scientific article published on January 1, 2014

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

scientific article published on 23 August 2011

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

scientific article

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

scientific article

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

scientific article

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

scientific article published in June 2010

Microarray scanner calibration curves: characteristics and implications

scientific article published on 15 July 2005

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

scientific article

Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site

scientific article published on August 13, 1998

Identification of a nucleotide binding site in HIV-1 integrase

scientific article published on April 14, 1998

The EDKB: an established knowledge base for endocrine disrupting chemicals

scientific article

Biomarkers for drug-induced liver injury

scientific article published on April 1, 2010

Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase: Identification of a Novel Four-Point Pharmacophore and Tetracyclines as Novel Inhibitors

scientific article published on December 1, 1997

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

scientific article published on 15 July 2005

Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

scientific article published on October 9, 2013

Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein

scientific article published on October 27, 2014

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

scientific article

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

scientific article published on 07 February 2020

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

scientific article

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

scientific article

Whole genome sequencing of 35 individuals provides insights into the genetic architecture of Korean population

scientific article

Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

scientific article

Versatility or Promiscuity: The Estrogen Receptors, Control of Ligand Selectivity and an Update on Subtype Selective Ligands

scientific article published on August 26, 2014

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

scientific article

Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets

scientific article

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine

scientific article published on 08 February 2013

Quantitative Structure-Activity Relationship Models for Predicting Drug-Induced Liver Injury Based on FDA-Approved Drug Labeling Annotation and Using a Large Collection of Drugs

scientific article published on August 31, 2013

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

scientific article

Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities

scientific article published on October 12, 2012

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

scientific article

Assessing QSAR Limitations - A Regulatory Perspective

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

scientific article

Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug development

scientific article published on October 1, 2011

Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds

scientific article

List of works by Huixiao Hong

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

Evaluation of external RNA controls for the assessment of microarray performance

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

Next-generation sequencing and its applications in molecular diagnostics

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

Development of public toxicogenomics software for microarray data management and analysis

Toward Predictive Models for Drug-Induced Liver Injury in Humans: Are we There Yet?

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

Microarray scanner calibration curves: characteristics and implications

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site

Identification of a nucleotide binding site in HIV-1 integrase

The EDKB: an established knowledge base for endocrine disrupting chemicals

Biomarkers for drug-induced liver injury

Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase: Identification of a Novel Four-Point Pharmacophore and Tetracyclines as Novel Inhibitors

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

Whole genome sequencing of 35 individuals provides insights into the genetic architecture of Korean population

Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

Versatility or Promiscuity: The Estrogen Receptors, Control of Ligand Selectivity and an Update on Subtype Selective Ligands

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine

Quantitative Structure-Activity Relationship Models for Predicting Drug-Induced Liver Injury Based on FDA-Approved Drug Labeling Annotation and Using a Large Collection of Drugs

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

Assessing QSAR Limitations - A Regulatory Perspective

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug development

Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds