List of works - Yuan-Tsong Chen

Medical genetics: a marker for Stevens-Johnson syndrome

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

scientific article

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

scientific article

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

scientific article

FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization.

scientific article

Mapping human genetic diversity in Asia

scientific article

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

scientific article

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan

scientific article published on March 24, 2011

Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis

article

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

scientific article

A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese

scientific article published on February 19, 2010

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

scientific article published on 15 July 2012

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Common Risk Allele in Aromatic Antiepileptic-Drug Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Han Chinese

scientific article published on March 1, 2010

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

scientific article published on 8 February 2012

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

scientific article

Human leukocyte antigens and drug hypersensitivity

scientific article (publication date: August 2007)

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

scientific article published on 14 September 2011

Long contiguous stretches of homozygosity in the human genome

scientific article published on 01 November 2006

Variant GADL1 and response to lithium therapy in bipolar I disorder

scientific article published on 25 December 2013

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

scientific journal article

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study

scientific journal article

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

scientific article

Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations

article

Type II collagen gene variants and inherited osteonecrosis of the femoral head

scientific article published in June 2005

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

scientific article published on 11 March 2008

Genetic determinants of warfarin dosing in the Han-Chinese population

scientific article published in December 2009

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

scientific article published on September 23, 2015

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome

scientific article

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

scientific article

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

scientific article

Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein

scientific article

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan

scientific article

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

scientific article

Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project

scientific article published on 18 October 2016

Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease

scientific article published on 01 May 2006

Genome-wide expression profiles of subchondral bone in osteoarthritis

scientific article published on January 2013

Genome-wide association study of treatment refractory schizophrenia in Han Chinese

scientific journal article

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility

scientific article

Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease

scientific article published in August 2005

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

scientific article published on January 2010

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease

scientific article

Mutations in the SLC2A10 gene cause arterial abnormalities in mice

scientific article published on 21 November 2008

Pharmacogenomics of adverse drug reactions: implementing personalized medicine

scientific article published on 19 August 2012

PrimerZ: streamlined primer design for promoters, exons and human SNPs

scientific article published on 30 May 2007

VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era

scientific article published on May 22, 2012

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

scientific article published on April 2016

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

scientific article published on 13 June 2016

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

scientific article published on 11 October 2016

List of works by Yuan-Tsong Chen

Medical genetics: a marker for Stevens-Johnson syndrome

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization.

Mapping human genetic diversity in Asia

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan

Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Common Risk Allele in Aromatic Antiepileptic-Drug Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Han Chinese

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

Human leukocyte antigens and drug hypersensitivity

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

Long contiguous stretches of homozygosity in the human genome

Variant GADL1 and response to lithium therapy in bipolar I disorder

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations

Type II collagen gene variants and inherited osteonecrosis of the femoral head

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

Genetic determinants of warfarin dosing in the Han-Chinese population

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project

Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease

Genome-wide expression profiles of subchondral bone in osteoarthritis

Genome-wide association study of treatment refractory schizophrenia in Han Chinese

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility

Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease

Mutations in the SLC2A10 gene cause arterial abnormalities in mice

Pharmacogenomics of adverse drug reactions: implementing personalized medicine

PrimerZ: streamlined primer design for promoters, exons and human SNPs

VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals