List of works - Ingrid B Borecki

Genetic and genomic discovery using family studies

scientific article published on September 2008

TP53, MDM2, NQO1, and Susceptibility to Cervical Cancer

scientific article published on March 3, 2010

Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study

scientific article

Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study

scientific article published on 09 February 2009

Multi-ethnic fine-mapping of 14 central adiposity loci

scientific article

Genetic evidence of assortative mating in humans

scholarly article

The Genetic Analysis Workshop 16 Problem 3: simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart Study

scientific article

Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?

scientific article

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

scientific article

Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states

scientific article published on 03 December 2008

The alpha 2-adrenergic receptor gene and body fat content and distribution: the HERITAGE Family Study.

scientific article

Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies

scientific article

Longitudinal and age trends of metabolic syndrome and its risk factors: the Family Heart Study

scientific article

Smoking, inflammatory patterns and postprandial hypertriglyceridemia

scientific article published on 13 August 2008

Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study

scientific article

Saturated fat intake modulates the association between an obesity genetic risk score and body mass index in two US populations

scientific article

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits

scientific article published on 28 October 2013

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians

scientific article

Effects of beta2-adrenergic receptor gene variants on adiposity: the HERITAGE Family Study

scientific article published in May 2003

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer

scientific article published on September 21, 2010

Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity

scientific article

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

Polyunsaturated fatty acids modulate the effect of TCF7L2 gene variants on postprandial lipemia

scientific article published on 13 January 2009

Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study

scientific article

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

scientific article published on 15 May 2017

Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

scientific article published on 29 November 2012

The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study

scientific article published on 18 February 2013

Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia

scientific article published on 8 July 2008

Chocolate consumption is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the NHLBI Family Heart Study

scientific article

The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions

scientific article published on 10 June 2008

Fenofibrate and metabolic syndrome

scientific article published on June 2010

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

scientific article published on 13 June 2018

CD83 gene polymorphisms increase susceptibility to human invasive cervical cancer

scientific article published on 01 December 2007

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

Sex-influenced association of nonalcoholic fatty liver disease with coronary heart disease.

scientific article published on 25 January 2013

Postprandial triacylglycerol metabolism is modified by the presence of genetic variation at the perilipin (PLIN) locus in 2 white populations

scientific article published in March 2008

"Predicting" parental longevity from offspring endophenotypes: data from the Long Life Family Study (LLFS).

scientific article

Impact of common variation in bone-related genes on type 2 diabetes and related traits

scientific article

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

scientific article

Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale

scientific article published on June 2017

Apolipoprotein A2 polymorphism interacts with intakes of dairy foods to influence body weight in 2 U.S. populations

scientific article published on 09 October 2013

Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status

scientific article published on 21 January 2011

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

scientific article

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries

scientific article published on 17 April 2013

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

scientific article published on 21 November 2016

Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).

scientific article published on 04 December 2013

List of works by Ingrid B Borecki

Genetic and genomic discovery using family studies

TP53, MDM2, NQO1, and Susceptibility to Cervical Cancer

Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study

Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study

Multi-ethnic fine-mapping of 14 central adiposity loci

Genetic evidence of assortative mating in humans

The Genetic Analysis Workshop 16 Problem 3: simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart Study

Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states

The alpha 2-adrenergic receptor gene and body fat content and distribution: the HERITAGE Family Study.

Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies

Longitudinal and age trends of metabolic syndrome and its risk factors: the Family Heart Study

Smoking, inflammatory patterns and postprandial hypertriglyceridemia

Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study

Saturated fat intake modulates the association between an obesity genetic risk score and body mass index in two US populations

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians

Effects of beta2-adrenergic receptor gene variants on adiposity: the HERITAGE Family Study

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer

Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Polyunsaturated fatty acids modulate the effect of TCF7L2 gene variants on postprandial lipemia

Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study

Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia

Chocolate consumption is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the NHLBI Family Heart Study

The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions

Fenofibrate and metabolic syndrome

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

CD83 gene polymorphisms increase susceptibility to human invasive cervical cancer

Common variants in Mendelian kidney disease genes and their association with renal function

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Sex-influenced association of nonalcoholic fatty liver disease with coronary heart disease.

Postprandial triacylglycerol metabolism is modified by the presence of genetic variation at the perilipin (PLIN) locus in 2 white populations

"Predicting" parental longevity from offspring endophenotypes: data from the Long Life Family Study (LLFS).

Impact of common variation in bone-related genes on type 2 diabetes and related traits

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale

Apolipoprotein A2 polymorphism interacts with intakes of dairy foods to influence body weight in 2 U.S. populations

Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).