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Authors whose works are in public domain in at least one jurisdiction

List of works by David Gallego-Ortega

1-46 of 46 results

Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study.

scientific article published on October 2007

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis

scientific article published in April 2017

Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment

scientific article

Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.

scientific article published on 5 March 2013

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

scientific article

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

scientific article published on February 2013

Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis.

scientific article published on July 2005

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells

scientific article

Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.

scientific article

TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer.

scientific article published on 11 November 2008

Involvement of human choline kinase alpha and beta in carcinogenesis: a different role in lipid metabolism and biological functions

scientific article

BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer

scientific article published on 16 July 2013

ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype

scientific article

The mammary cellular hierarchy and breast cancer

scientific article published on July 31, 2014

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

scientific article published on 22 December 2015

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

scientific article (publication date: December 2015)

Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

scientific article

MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib

scientific article published on 08 December 2016

Evidence of p38γ and p38δ involvement in cell transformation processes

scientific article published on 10 May 2011

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

scientific article published in October 2017

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.

scientific article published on 7 November 2017

The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.

scientific article

Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology

ELF5 isoform expression is tissue-specific and significantly altered in cancer

scientific article

Droplet-based single cell RNAseq tools: a practical guide

scientific article published on 01 May 2019

MASTL overexpression promotes chromosome instability and metastasis in breast cancer.

scientific article

Generation and characterization of monoclonal antibodies against choline kinase alpha and their potential use as diagnostic tools in cancer.

scientific article

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

scientific article published in Nature Communications

The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy

scientific article published on 01 July 2017

Andy's Algorithms: new automated digital image analysis pipelines for FIJI.

scientific article published on 16 November 2017

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.

scientific article published on 8 November 2017

Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer

scientific article published on 27 February 2020

Static droplet array for culturing single live adherent cells in an isolated chemical microenvironment

scientific article published on 01 July 2018

Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells

scientific article published on 01 February 2020

ELF5 modulates the estrogen receptor cistrome in breast cancer

scientific article published on 02 January 2020

ALTEN: A High‐Fidelity Primary Tissue‐Engineering Platform to Assess Cellular Responses Ex Vivo

Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer

scientific article

Challenges in blood fractionation for cancer liquid biopsy: how can microfluidics assist?

Pleiotrophin drives a prometastatic immune niche in breast cancer

scientific article published in 2023

Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion.

scientific article published on 23 November 2017

MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma

scientific article published on 18 November 2019

Gradient-sized control of tumor spheroids on a single chip

scientific article published on 12 November 2019

Capillary-assisted microfluidic biosensing platform captures single cell secretion dynamics in nanoliter compartments

scientific article published on 19 February 2020

Genomic Cytometry Editorial

scientific article published on 22 August 2020

Mammary Tumor Organoid Culture in Non-Adhesive Alginate for Luminal Mechanics and High-Throughput Drug Screening

scientific article published on 08 September 2021

Genomic Cytometry and New Modalities for Deep Single-Cell Interrogation

scientific article published on 14 August 2020