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List of works by Jürgen Machann

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Identification and characterization of metabolically benign obesity in humans

scientific article
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects

scientific article
Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance

scientific article published on 11 June 2009
Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans

scientific article
Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

scientific article published on 03 August 2009
Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans

scientific article
Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

scientific article published in April 2003
Relationship of serum adiponectin and leptin concentrations with body fat distribution in humans

scientific article published in March 2003
High circulating retinol-binding protein 4 is associated with elevated liver fat but not with total, subcutaneous, visceral, or intramyocellular fat in humans

scientific article published on 26 January 2007
Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans

scientific article published on 15 December 2008
Standardized assessment of whole body adipose tissue topography by MRI

scientific article published on 01 April 2005
High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease

scientific article
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

scientific article published on 5 October 2005
Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study

scientific article published in March 2010
The impact of liver fat vs visceral fat in determining categories of prediabetes

scientific article published on 23 January 2010
Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo

scientific article published on 28 May 2009
Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity

scientific article published in June 2009
Effects of supplemented isoenergetic diets differing in cereal fiber and protein content on insulin sensitivity in overweight humans.

scientific article
Circulating palmitoleate strongly and independently predicts insulin sensitivity in humans

scientific article
Effects of a lifestyle intervention in metabolically benign and malign obesity

scientific article published on 21 December 2010
Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss

scientific article published on 29 May 2008
Relationships of circulating sex hormone-binding globulin with metabolic traits in humans

scientific article
Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression

scientific article published on 13 January 2010
Intramyocellular lipids and insulin resistance

scientific article published on July 2004
Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study

scientific article published on 6 July 2005
Liver fat content determined by magnetic resonance imaging and spectroscopy

scientific article published on April 2010
Hepatic lipid accumulation in healthy subjects: A comparative study using spectral fat-selective MRI and volume-localized1H-MR spectroscopy

scientific article published in 2006
Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans

scientific article published on 27 May 2016
(1)H MR spectroscopy of skeletal muscle, liver and bone marrow

scientific article
Lifestyle intervention in individuals with normal versus impaired glucose tolerance

scientific article published on July 2007
Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques

scientific article published in May 2008
Follow-up whole-body assessment of adipose tissue compartments during a lifestyle intervention in a large cohort at increased risk for type 2 diabetes

scientific article published on 16 August 2010
Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation

scientific article
The secretion pattern of perivascular fat cells is different from that of subcutaneous and visceral fat cells

scientific article published on 13 February 2012
Fast elevation of the intramyocellular lipid content in the presence of circulating free fatty acids and hyperinsulinemia: a dynamic 1H-MRS study

scientific article
MRI of muscular fat.

scientific article
Reduced cortical thickness associated with visceral fat and BMI.

scientific article
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver

scientific article published on 20 March 2013
Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans

scientific article
Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction

scientific article published on 20 August 2008
T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin

scientific article
The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans

scientific article
A moderate weight reduction through dietary intervention decreases hepatic fat content in patients with non-alcoholic fatty liver disease (NAFLD): a pilot study

scientific article published on 28 April 2012
Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults

scientific article
Utilisation of intramyocellular lipids (IMCLs) during exercise as assessed by proton magnetic resonance spectroscopy (1H-MRS)

scientific article published on 01 February 2001
Genetic Variations inPPARDandPPARGC1ADetermine Mitochondrial Function and Change in Aerobic Physical Fitness and Insulin Sensitivity during Lifestyle Intervention

scientific article published in May 2007
Lipid content in the musculature of the lower leg assessed by fat selective MRI: intra- and interindividual differences and correlation with anthropometric and metabolic data

scientific article
Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 17 February 2014
Topography mapping of whole body adipose tissue using A fully automated and standardized procedure

scientific article published in February 2010
Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes

scientific article

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