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List of works by Fred Saad

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Abiraterone and increased survival in metastatic prostate cancer

scientific article (publication date: 26 May 2011)
Abiraterone in metastatic prostate cancer without previous chemotherapy

scientific article published on 10 January 2013
Enzalutamide in metastatic prostate cancer before chemotherapy

scientific article published in June 2014
A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma

scientific article
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study

scientific article published on September 18, 2012
Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer

scientific article
Denosumab in men receiving androgen-deprivation therapy for prostate cancer

scientific article
Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3

scientific article published on 16 January 2015
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial

scientific article published on November 15, 2011
Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: a combined analysis of 3 pivotal, randomised, phase 3 trials

scientific article
Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors

scientific article published in January 2005
Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid

scientific article published on 27 June 2005
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

scientific article
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article
Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

article
Pathologic fractures correlate with reduced survival in patients with malignant bone disease

scientific article published on 01 October 2007
Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer

scientific article published in May 2005
Intermittent androgen suppression for rising PSA level after radiotherapy

scientific article
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer

scientific article published in November 2007
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer

scientific article
Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer

scientific article published on 8 February 2018
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer

scientific article published in August 2009
Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer

scientific article published on 31 October 2016
Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer.

scientific article published on 23 August 2010
Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302).

scientific article published on 6 March 2014
Systemic therapy in men with metastatic castration-resistant prostate cancer:American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline

scientific article
Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial

scientific article published on 8 November 2013
Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid

scientific article published in July 2008
Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.

scientific article
Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer

scientific article published on 01 June 2018
uPM3, a new molecular urine test for the detection of prostate cancer.

scientific article published on August 2004
Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients.

scientific article published on 22 June 2009
Cancer treatment-induced bone loss in breast and prostate cancer

scientific article published on 27 October 2008
Radical versus partial nephrectomy

scientific article published on 01 April 2009
Castration-resistant prostate cancer: from new pathophysiology to new treatment targets.

scientific article published on 24 June 2009
Radium-223 and concomitant therapies in patients with metastatic castration-resistant prostate cancer: an international, early access, open-label, single-arm phase 3b trial

scientific article
Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance).

scientific article published on 03 March 2014
Management of prostate cancer in older men: recommendations of a working group of the International Society of Geriatric Oncology

scientific article published on 25 March 2010
Denosumab and Bone Metastasis–Free Survival in Men With Nonmetastatic Castration-Resistant Prostate Cancer: Exploratory Analyses by Baseline Prostate-Specific Antigen Doubling Time

scientific article published on September 16, 2013
Phase III Study of Cabozantinib in Previously Treated Metastatic Castration-Resistant Prostate Cancer: COMET-1.

scientific article
A Nomogram Predicting 10-Year Life Expectancy in Candidates for Radical Prostatectomy or Radiotherapy for Prostate Cancer

scientific article published on 01 August 2007
New therapies for castration-resistant prostate cancer: efficacy and safety

scientific article published on 04 May 2011
Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

scientific article published on 18 April 2013
Regulation of E2Fs and senescence by PML nuclear bodies.

scientific article published on January 2011
Multicenter phase II study of combined neoadjuvant docetaxel and hormone therapy before radical prostatectomy for patients with high risk localized prostate cancer

scientific article published on 12 June 2008
Randomized, placebo-controlled, phase III trial of sunitinib plus prednisone versus prednisone alone in progressive, metastatic, castration-resistant prostate cancer.

scientific article
SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer

scientific article published on 16 December 2009
Randomized phase II trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c.

scientific article
Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology

scientific article
Castration-Resistant Prostate Cancer: From New Pathophysiology to New Treatment

scientific article published on August 11, 2013

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