List of works - Margaret Spitz

Somatic mutations affect key pathways in lung adenocarcinoma

scientific article

Characterizing the cancer genome in lung adenocarcinoma

scientific article

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

scientific article

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

scientific article

Telomere dysfunction: a potential cancer predisposition factor

scientific article

Detectable clonal mosaicism and its relationship to aging and cancer

journal article published in 2012

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms

scientific article

The landscape of recombination in African Americans

scientific article

A risk model for prediction of lung cancer

scientific article published on 01 May 2007

Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study

scientific article

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer

scientific article published on 28 October 2008

Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

scientific article

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scientific journal article

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma

scientific article published on 29 July 2008

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

scientific article

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

scientific article

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity

scientific article published in May 2002

Genetic susceptibility to lung cancer: the role of DNA damage and repair.

scientific article

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk

scientific article published on 11 July 2011

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

scientific article published on 12 June 2017

Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer

scientific article published on 9 September 2008

An analysis of DNA repair as a determinant of survival in patients with non-small-cell lung cancer

scientific article

Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

scientific article published on February 3, 2012

Smoking, DNA repair capacity and risk of nonsmall cell lung cancer

scientific article published in October 2003

XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity

scientific article

An expanded risk prediction model for lung cancer

scientific article

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways

scientific article

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma

scientific article published on 01 February 2003

Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States

scientific article published on May 2009

Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

scientific article

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk

scientific article

An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology

scientific article published on March 2004

Never smokers and lung cancer risk: a case-control study of epidemiological factors.

scientific article

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.

scientific article

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Projecting individualized probabilities of developing bladder cancer in white individuals

scientific article published on 01 November 2007

Characterization of large structural genetic mosaicism in human autosome

journal article published in 2015

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

scientific article

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

scientific article published in May 2015

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

scientific article

Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma

scientific article

Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study

scientific article published on October 2008

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck

scientific article

Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture

scientific article

Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck

scientific article published on September 2006

IARC monographs: 40 years of evaluating carcinogenic hazards to humans

journal article published in 2015

Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation.

scientific article

List of works by Margaret Spitz

Somatic mutations affect key pathways in lung adenocarcinoma

Characterizing the cancer genome in lung adenocarcinoma

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

Telomere dysfunction: a potential cancer predisposition factor

Detectable clonal mosaicism and its relationship to aging and cancer

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms

The landscape of recombination in African Americans

A risk model for prediction of lung cancer

Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer

Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity

Genetic susceptibility to lung cancer: the role of DNA damage and repair.

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer

An analysis of DNA repair as a determinant of survival in patients with non-small-cell lung cancer

Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

Smoking, DNA repair capacity and risk of nonsmall cell lung cancer

XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity

An expanded risk prediction model for lung cancer

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma

Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States

Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk

An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology

Never smokers and lung cancer risk: a case-control study of epidemiological factors.

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Projecting individualized probabilities of developing bladder cancer in white individuals

Characterization of large structural genetic mosaicism in human autosome

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma

Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck

Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture

Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck

IARC monographs: 40 years of evaluating carcinogenic hazards to humans

Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation.