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List of works by Federico Innocenti

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Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).

scientific article
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

scientific article
Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial.

scientific article
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics

scientific article
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

scientific article
Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

scientific article
Ethnic differences and functional analysis of MET mutations in lung cancer

scientific article published on September 2009
Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups

scientific article published on December 2002
Clinical pharmacology and pharmacogenetics of gemcitabine

scientific article
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine

scientific article
Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer

scientific article published on 28 December 2009
A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter.

scientific article
Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.

scientific article published on January 2003
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303

scientific journal article
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

scientific article published on 08 August 2016
Dose-Finding and Pharmacokinetic Study to Optimize the Dosing of Irinotecan According to the UGT1A1 Genotype of Patients With Cancer

scientific article published on June 23, 2014
Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines

scientific article published on November 2007
Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene

scientific article published on August 2008
Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism.

scientific article published on March 2003
Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.

scientific article published in May 2005
Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer

scientific article
The role of pharmacogenetics in cancer therapeutics

scientific article published on July 2006
Insights, challenges, and future directions in irinogenetics

scientific article published on June 2007
The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity

scientific article published on 01 January 2007
Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor-Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance)

scientific article published on 02 May 2016
Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes

scientific article published in September 2005
Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping

scientific article published on 01 December 2006
A genome-wide integrative study of microRNAs in human liver

scientific article
Mutational Analysis of Patients With Colorectal Cancer in CALGB/SWOG 80405 Identifies New Roles of Microsatellite Instability and Tumor Mutational Burden for Patient Outcome

scientific article published on 13 March 2019
Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet?

scientific article published on June 2008
Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.

scientific article published on 05 February 2013
Lack of association between common polymorphisms in UGT1A9 and gene expression and activity

scientific article published on 30 August 2007
Impact of Consensus Molecular Subtype on Survival in Patients With Metastatic Colorectal Cancer: Results From CALGB/SWOG 80405 (Alliance)

scientific article published on 01 May 2019
Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy.

scientific article published on 31 January 2014
UGT pharmacogenomics: implications for cancer risk and cancer therapeutics

scientific article published on 01 August 2003
Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters

scientific article published on 23 September 2010
Pharmacogenomics: road to anticancer therapeutics nirvana?

scientific article published on September 29, 2003
In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes

scientific article
Searching for tissue-specific expression pattern-linked nucleotides of UGT1A isoforms

scientific article published on 25 April 2007
Implications of genome‐wide association studies in cancer therapeutics

scientific article published on September 1, 2013
25-Hydroxyvitamin D levels and survival in advanced pancreatic cancer: findings from CALGB 80303 (Alliance).

scientific article
The use of genomic information to optimize cancer chemotherapy

scientific article
"Irinogenetics" and UGT1A: from genotypes to haplotypes

scientific article published on June 2004
A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital

scientific article published in November 2004
Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive diseas

scientific article published on 4 October 2010
Irinogenetics: what is the right star?

scientific article published on 24 April 2006
A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

scientific article published in April 2018
Genomic Characterization of Metformin Hepatic Response

scientific article
ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.

scientific article published on 8 September 2015
Bridging genomics research between developed and developing countries: the Genomic Medicine Alliance

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