List of works - Peter Almgren

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

scientific article (publication date: June 2007)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Cardiovascular morbidity and mortality associated with the metabolic syndrome

scientific article published on April 2001

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Clinical risk factors, DNA variants, and the development of type 2 diabetes

scientific article

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

scientific article published in August 2007

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Novel and conventional biomarkers for prediction of incident cardiovascular events in the community

scientific article

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes

scientific article published in January 2005

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

scientific article published on 01 October 2006

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

scientific article published in March 2018

Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes

scientific article published on 8 May 2014

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes

scientific article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

scientific article published in May 2004

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study

scientific article published on June 2000

Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins

scientific article

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

scientific article

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

scientific article

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation

scientific article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Plasma copeptin and the risk of diabetes mellitus

scientific article published on 03 May 2010

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

scientific article (publication date: November 2007)

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

article

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

scientific article published on 6 March 2013

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

article by Peter Almgren et al published 9 August 2011 in Diabetologia

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

article

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

scientific article

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study

scientific article

Genetic prediction of future type 2 diabetes

scientific article

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

scientific article

The metabolic syndrome influences the risk of chronic complications in patients with type II diabetes

scientific article

Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity

scientific article

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

scientific article published on 06 February 2002

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

scientific article

The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure

scientific article

Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis

scientific article

List of works by Peter Almgren

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Cardiovascular morbidity and mortality associated with the metabolic syndrome

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Clinical risk factors, DNA variants, and the development of type 2 diabetes

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Novel and conventional biomarkers for prediction of incident cardiovascular events in the community

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study

Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Plasma copeptin and the risk of diabetes mellitus

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

A central role for GRB10 in regulation of islet function in man.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study

Genetic prediction of future type 2 diabetes

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

The metabolic syndrome influences the risk of chronic complications in patients with type II diabetes

Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure

Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants