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Authors whose works are in public domain in at least one jurisdiction

List of works by John A. Porco

51-100 of 112 results

Syntheses of Dimeric Tetrahydroxanthones with Varied Linkages: Investigation of "Shapeshifting" Properties

scientific article

Skeletal diversity via cationic rearrangements of substituted dihydropyrans

scientific article

Total Synthesis and Stereochemical Assignment of (±)-Sorbiterrin A

scientific article published on February 24, 2014

Development of a Potent and Selective HDAC8 Inhibitor

scientific article published on September 2016

Studies toward the Synthesis of the Epoxykinamycin FL-120B′: Discovery of a Decarbonylative Photocyclization

scientific article published on May 9, 2012

Polymer-assisted solution-phase (PASP) Suzuki couplings employing an anthracene-tagged palladium catalyst

scientific article published in December 2003

Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets

scientific article published in November 2006

A photochemical flow reactor for large scale syntheses of aglain and rocaglate natural product analogues

scientific article published on 11 June 2017

Bcl-XL, but not Bcl-2, can protect human B-lymphoma cell lines from parthenolide-induced apoptosis

scientific article published on December 6, 2011

Synthesis of photoactivatable acyclic analogues of the lobatamides

scientific article published in April 2005

Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors

scientific article published on 10 September 2019

1,2-dihydroisoquinolines as templates for cascade reactions to access isoquinoline alkaloid frameworks

scientific article

Synthesis of chamaecypanone C analogues from in situ-generated cyclopentadienones and their biological evaluation.

scientific article

Total synthesis of (±)-sorocenol B employing nanoparticle catalysis

scientific article

High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics

scientific article published on 01 September 2018

Total synthesis of the interleukin-1beta converting enzyme inhibitor EI-1941-2 using tandem oxa-electrocyclization/oxidation1

scientific article published on 01 June 2006

Metal-Catalyzed Cascade Rearrangements of 3-Alkynyl Flavone Ethers

scientific article published on April 10, 2013

Electron transfer-initiated Diels-Alder cycloadditions of 2'-hydroxychalcones

scientific article

Synthesis and V-ATPase inhibition of simplified lobatamide analogues

scientific article published in September 2002

Stereochemical and skeletal diversity employing pipecolate ester scaffolds

scientific article published on 17 March 2007

Gold Catalyzed Cyclization of Alkyne-Tethered Dihydropyrimidones

scientific article published on July 13, 2011

Synthetic cyclohexenyl chalcone natural products possess cytotoxic activities against prostate cancer cells and inhibit cysteine cathepsins in vitro

scientific article published on November 19, 2011

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

scientific article published in Scientific Reports

Multidimensional Screening and Methodology Development for Condensations Involving Complex 1,2-Diketones

scientific article published on July 1, 2010

Syntheses of (+)-30-epi-, (-)-6-epi-, (±)-6,30-epi-13,14-Didehydroxyisogarcinol and (±)-6,30-epi-Garcimultiflorone A Utilizing Highly Diastereoselective, Lewis Acid-Controlled Cyclizations

scientific article published on 16 October 2016

Skeletal diversity through radical cyclization of tetrahydropyridine scaffolds

scientific article

Synthesis of a polymer-supported anthracene and its application as a dienophile scavenger

scientific article published in March 2004

Total Synthesis of Aurofusarin: Studies on the Atropisomeric Stability of Bis-Naphthoquinones

scientific article published on 9 January 2018

Asymmetric Synthesis of Gonytolide A: Strategic Use of an Aryl Halide Blocking Group for Oxidative Coupling

scientific article published on 16 April 2018

Nucleophilic addition to N-phosphinylimines by rare-earth-metal triflate/trifluoroacetic anhydride activation

scientific article

Eucalyptusdimers A-C, Dimeric Phloroglucinol-Phellandrene Meroterpenoids from Eucalyptus robusta

scientific article published on 08 August 2018

Biomimetic Total Synthesis of (±)-Griffipavixanthone via a Cationic Cycloaddition-Cyclization Cascade

scientific article

Rocaglates as dual-targeting agents for experimental cerebral malaria

scientific article published on 20 February 2018

Asymmetric Dearomatization/Cyclization Enables Access to Polycyclic Chemotypes

scientific article published on October 2016

Asymmetric Syntheses of the Flavonoid Diels–Alder Natural Products Sanggenons C and O

scientific article published on January 19, 2016

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

scientific article published on 13 November 2019

Regiodivergent Photocyclization of Dearomatized Acylphloroglucinols: Asymmetric Syntheses of (-)-Nemorosone and (-)-6-epi-Garcimultiflorone A

scientific article published on 02 July 2019

Enantioselective synthesis of linear polypropionate arrays using anthracene-tagged organosilanes

scientific article published in September 2005

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors

scientific article published on 30 July 2019

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

scientific article published on 22 December 2020

A Cycloisomerization/Friedel–Crafts Alkylation Strategy for the Synthesis of Pyrano[3,4-b]indoles

scientific article published on July 8, 2011

Chemical Synthesis Enables Structural Reengineering of Aglaroxin C Leading to Inhibition Bias for Hepatitis C Viral Infection

scientific article published on 11 January 2019

eIF4A Inhibitors Suppress Cell-Cycle Feedback Response and Acquired Resistance to CDK4/6 Inhibition in Cancer

scientific article published on 08 August 2019

Synthesis of the epoxyquinol dimer RKB-3564 D: utilization of an alkoxysilanol to promote [4 + 4] dimerization

scientific article

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris

scientific article published on 10 March 2020

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

scientific article published on 01 February 2020

Inhibiting Translation as a Novel Strategy to Target Multiple Myeloma

scholarly article

Biomimetic Synthesis of Meroterpenoids by Dearomatization-Driven Polycyclization

scientific article published on 25 September 2019

Synthesis and Multiplexed Activity Profiling of Synthetic Acylphloroglucinol Scaffolds

scientific article published on 23 September 2020

Asymmetric Synthesis of Griffipavixanthone Employing a Chiral Phosphoric Acid-Catalyzed Cycloaddition

scientific article published on 26 December 2018