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List of works by Izzy Jayasinghe

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Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes

scientific article
Organization of ryanodine receptors, transverse tubules, and sodium-calcium exchanger in rat myocytes.

scientific article
4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues

scientific article
Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media.

scientific article published on January 2009
Comparison of the organization of T-tubules, sarcoplasmic reticulum and ryanodine receptors in rat and human ventricular myocardium

scientific article published on 01 May 2012
Three-dimensional high-resolution imaging of cardiac proteins to construct models of intracellular Ca2+ signalling in rat ventricular myocytes.

scientific article published on 12 January 2009
Nanoscale analysis of ryanodine receptor clusters in dyadic couplings of rat cardiac myocytes

scientific article published on 20 December 2014
True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors.

scientific article published in January 2018
Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

scientific article published on 21 October 2016
Revealing T-Tubules in Striated Muscle with New Optical Super-Resolution Microscopy Techniquess

scientific article published on 7 January 2015
Super-resolution fluorescence imaging to study cardiac biophysics: α-actinin distribution and Z-disk topologies in optically thick cardiac tissue slices.

scientific article
A new twist in cardiac muscle: dislocated and helicoid arrangements of myofibrillar z-disks in mammalian ventricular myocytes.

scientific article published on 4 January 2010
Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging

scientific article published on October 2014
Combining confocal and single molecule localisation microscopy: A correlative approach to multi-scale tissue imaging.

scientific article published on 24 March 2015
Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle

scientific article published on June 26, 2013
Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise.

scientific article published on 13 February 2017
Algorithmic corrections for localization microscopy with sCMOS cameras - characterisation of a computationally efficient localization approach.

scientific article published in May 2017
Shining New Light on the Structural Determinants of Cardiac Couplon Function: Insights From Ten Years of Nanoscale Microscopy

scientific article published on 22 October 2018
Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers.

scientific article published on June 2013
Transverse tubule remodelling: a cellular pathology driven by both sides of the plasmalemma?

scientific article published on 10 July 2017
Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

article
Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies

scientific article published on 15 May 2019
Correlative Single-Molecule Localization Microscopy and Confocal Microscopy.

scientific article published in January 2017
Resolving the structural basis of cardiac excitation-contraction coupling

2010 doctoral thesis by Izzy Jayasinghe at University of Auckland
Dismantling barriers faced by women in STEM

scientific article published on 27 October 2022
Expansion microscopy reveals subdomains inC. elegansgerm granules

scientific article published on 7 February 2023
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

scientific article published in May 2023
Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads

scientific article published on 3 October 2022
A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types

scientific article published on 12 October 2020
Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes

Conversations with LGBT+ scientists about visibility, leadership and climbing the career ladder

scientific article published on 15 February 2022
A Review of Barriers Women Face in Research Funding Processes in the UK

Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time

Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy

Molecular-scale 3D visualisation of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads

Cysteine post‐translational modifications regulate protein interactions of caveolin‐3

scientific article published on 11 March 2024
Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics

scientific article published on 3 October 2022
Cysteine post-translational modifications regulate protein interactions of caveolin-3

Geometry-preserving Expansion Microscopy microplates enable high fidelity nanoscale distortion mapping

Multi-scale approaches for the simulation of cardiac electrophysiology: I - Sub-cellular and stochastic calcium dynamics from cell to organ

scientific article published on 29 February 2020
Expansion microscopy reveals subdomains in C. elegans germ granules

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