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List of works by Sébastien Lenglet

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Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

scientific article published on 11 July 2012
Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics

scientific article published on 26 May 2011
The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.

scientific article
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction

scientific article published on 14 May 2012
Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke

scientific article
Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

scientific article published on 01 March 1998
Role of matrix metalloproteinase-8 in atherosclerosis

scientific article published on 9 January 2013
Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice

scientific article published on 19 December 2012
Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

scientific article published on 06 February 2014
Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

scientific article published on 27 March 2014
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

scientific article published on 7 November 2013
Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability.

scientific article published on 24 November 2011
Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury

scientific article published on 23 February 2011
Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

article published in 2015
Three-dimensional imaging MS of lipids in atherosclerotic plaques: Open-source methods for reconstruction and analysis.

scientific article published on 9 March 2016
Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.

scientific article
Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury

scientific article published on 4 April 2016
Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice

scientific article
Role of neurotransmitters and neuropeptides in the regulation of the adrenal cortex

scientific article published on August 1, 2001
Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.

scientific article published on 23 September 2017
Role of the T-type calcium channel CaV3.2 in the chronotropic action of corticosteroids in isolated rat ventricular myocytes

scientific journal article
Mas receptor deficiency is associated with worsening of lipid profile and severe hepatic steatosis in ApoE-knockout mice.

scientific article published on 2 October 2013
Impact of propofol anaesthesia on cytokine expression profiles in the developing rat brain: a randomised placebo-controlled experimental in-vivo study

scientific article published in May 2015
Treatment with Evasin-3 abrogates neutrophil-mediated inflammation in mouse acute pancreatitis

scientific article
Molecular imaging of matrix metalloproteinases in atherosclerotic plaques

scientific article published on 25 January 2012
Role of Matrix Metalloproteinases in Animal Models of Ischemic Stroke

scientific article published on January 1, 2015
Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome.

scientific article published on 25 January 2011
Methylene blue: potential use of an antique molecule in vasoplegic syndrome during cardiac surgery.

scientific article published on December 2011
Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways.

scientific article published on 20 November 2014
Alpha-fetoprotein: a controversial prognostic biomarker for small hepatocellular carcinoma

scientific article published on January 2013
Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis.

scientific article published on 28 July 2016
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response

scientific article published on 25 April 2015
Alamandine abrogates neutrophil degranulation in atherosclerotic mice

scientific article
Rat glomerulosa cells express functional 5-HT7 receptors

scientific article published on 01 November 2000
Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis

scientific article published on 21 September 2016
Vitamin D receptor is expressed within human carotid plaques and correlates with pro-inflammatory M1 macrophages

scientific article published on 20 August 2016
Pharmacological and Functional Characterization of Muscarinic Receptors in the Frog Pars Intermedia1

scientific article published on August 1, 1998
Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function.

scientific article published on 13 December 2016
Role of cAMP/PKA pathway and T-type calcium channels in the mechanism of action of serotonin in human adrenocortical cells

scientific article published on 12 October 2016
Multiplex quantitative imaging of human myocardial infarction by mass spectrometry-immunohistochemistry

scientific article published on 19 March 2018
Update on the Pathophysiological Role of Intracellular Signaling Pathways in Atherosclerotic Plaques and Ischemic Myocardium

scientific article published on May 1, 2012
Molecular design based on 3D pharmacophores. Applications to 5-HT7 receptors.

scientific article
Treatment with CB2 agonist JWH-133 reduces histological features associated with erectile dysfunction in hypercholesterolemic mice.

scientific article
Treatment with sulphated galactan inhibits macrophage chemotaxis and reduces intraplaque macrophage content in atherosclerotic mice

scientific article

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