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List of works by Romano Danesi

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MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.

scientific article
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

scientific article
Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

scientific article
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer

scientific article
Pharmacogenomics of ABC transporters and its role in cancer chemotherapy.

scientific article
EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis

scientific article published on December 2012
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

scientific article published on 10 January 2008
The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients.

scientific article published on 26 August 2016
Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells

scientific article
The pharmacological bases of the antiangiogenic activity of paclitaxel

scientific article published on 07 February 2013
Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice.

scientific article published on 05 May 2011
Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies

scientific article published on 28 September 2011
Polycomb genes and cancer: time for clinical application?

scientific article
Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer

scientific article
Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib

scientific article
DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis

scientific article published on August 2013
Pharmacokinetic-pharmacodynamic relationships of the anthracycline anticancer drugs.

scientific article
Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

scientific article published in October 2002
Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells

scientific article
Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer

scientific article published on June 2006
EPMA position paper in cancer: current overview and future perspectives

scientific article published on 15 April 2015
Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines.

scientific article published on May 2004
Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA.

scientific article published on 20 January 2016
BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer

scientific article published on April 2011
Association of polymorphisms in AKT1 and EGFR with clinical outcome and toxicity in non-small cell lung cancer patients treated with gefitinib.

scientific article published on 16 February 2010
Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

scientific article published on 21 July 2009
Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane.

scientific article
A polymorphism in a transporter of testosterone is a determinant of androgen independence in prostate cancer.

scientific article published on 04 June 2008
CYP2D6 polymorphisms and the impact on tamoxifen therapy

scientific article
Dose-finding study and pharmacokinetics of epirubicin and paclitaxel over 3 hours: a regimen with high activity and low cardiotoxicity in advanced breast cancer

scientific article published on 01 July 1997
Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer.

scientific article
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

scientific article published on 2 March 2012
Prolonged fixed dose rate infusion of gemcitabine with autologous haemopoietic support in advanced pancreatic adenocarcinoma.

scientific article published on July 2005
Cancer stem cell epigenetics and chemoresistance.

scientific article published on October 2009
Cardiac toxicity of antineoplastic anthracyclines.

scientific article
Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients

scientific article published on 01 August 2000
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer.

scientific article published on 8 December 2010
Pharmacogenetics of anticancer drug sensitivity in non-small cell lung cancer

scientific article
Circulating DNA in diagnosis and monitoring EGFR gene mutations in advanced non-small cell lung cancer

scientific article published on October 1, 2015
Suramin, a novel antitumor compound.

scientific article published on December 1990
Pharmacological issues of linezolid: an updated critical review

scientific article published on July 2010
Key concepts and critical issues on epoetin and filgrastim biosimilars. A position paper from the Italian Society of Hematology, Italian Society of Experimental Hematology, and Italian Group for Bone Marrow Transplantation.

scientific article published on July 2011
Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.

scientific article
Suramin in adrenal cancer: modulation of steroid hormone production, cytotoxicity in vitro, and clinical antitumor effect.

scientific article published on August 1990
Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role

scientific article published on 01 January 1993
Synergistic antitumor activity of ZD6474, an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, with gemcitabine and ionizing radiation against pancreatic cancer.

scientific article published on December 2006
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells.

scientific article published in June 1998
Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients.

scientific article
The emerging role of histone lysine demethylases in prostate cancer

scientific article
5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

scientific article published in May 2008

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