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List of works by Malcolm Macleod

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Stroke

scientific article 2008
Increasing value and reducing waste in research design, conduct, and analysis

scientific article
Can animal models of disease reliably inform human studies?

scientific article
A call for transparent reporting to optimize the predictive value of preclinical research

scientific article
Biomedical research: increasing value, reducing waste

scientific article
Comparison of treatment effects between animal experiments and clinical trials: systematic review

scientific article published on 15 December 2006
Pooling of animal experimental data reveals influence of study design and publication bias

scientific article
Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis

scientific article
Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

scientific article
How can we improve the pre-clinical development of drugs for stroke?

scientific article published on 31 August 2007
Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis

scientific article published on 3 May 2007
Increasing value and reducing waste in biomedical research regulation and management

scientific article (publication date: 11 January 2014)
Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality

scientific article
Good laboratory practice: preventing introduction of bias at the bench

scientific article published on 14 August 2008
Meta-analysis of data from animal studies: a practical guide

scientific article
Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach

scientific article published on 31 January 2008
Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia

scientific article
Evaluation of excess significance bias in animal studies of neurological diseases

scientific article
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

scientific article published on 13 October 2015
Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials?

scientific article
Systematic review and metaanalysis of the efficacy of FK506 in experimental stroke

scientific article
Improving the translational hit of experimental treatments in multiple sclerosis

scientific article published on 04 August 2010
Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke

scientific article
Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis

scientific article published in October 2000
Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis

scientific article
Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis

scientific article
Systematic review and stratified meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke

scientific article published on July 2009
The future of restorative neurosciences in stroke: driving the translational research pipeline from basic science to rehabilitation of people after stroke

scientific article (publication date: February 2009)
Animal models of bone cancer pain: systematic review and meta-analyses

scientific article published on 07 March 2013
Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically

scientific article
Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

scientific article
Stem cell-based therapy for experimental stroke: a systematic review and meta-analysis.

scientific article published on 12 June 2012
A concerted appeal for international cooperation in preclinical stroke research

scientific article (publication date: June 2013)
Stem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studies

scientific article
Systematic review and meta-analysis of the efficacy of melatonin in experimental stroke

scientific article
Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: systematic review and meta-analysis of large animal studies

scientific article published on 03 September 2014
EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke

scientific article published on 15 May 2014
Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies.

scientific article published on 17 February 2016
Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis

scientific article
Bringing rigour to translational medicine

scientific article published on November 19, 2013
Dopamine agonists in animal models of Parkinson's disease: a systematic review and meta-analysis

scientific article published on 04 March 2011
Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis

scientific article published on January 2014
Treatment of intracerebral hemorrhage in animal models: meta-analysis

scientific article published in February 2011
Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice

scientific article published on 23 June 2009
A systematic review and meta-analysis of erythropoietin in experimental stroke

scientific article
Reprint: Good laboratory practice: preventing introduction of bias at the bench

scientific article published on 17 September 2008
Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?

scientific article published on January 2013
Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke

scientific article
Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing

scientific article
Preclinical studies of human disease: time to take methodological quality seriously

scientific article published on 29 April 2011

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