List of works - Ava Kwong

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

scientific article

Association analysis identifies 65 new breast cancer risk loci

scientific article published on 23 October 2017

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Circulating microRNAs as specific biomarkers for breast cancer detection.

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

scientific article

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018

First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2,251 patients.

scientific article published on 5 September 2010

Circulating cell-free miRNAs as biomarker for triple-negative breast cancer

scientific article

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

scientific article

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Comparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testing

scientific article

Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer.

scientific article published on 15 March 2012

The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study.

scientific article published on 30 August 2013

Validation of the Chinese version of the short-form Supportive Care Needs Survey Questionnaire (SCNS-SF34-C).

scientific article published on 29 September 2010

MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells.

scientific article published on 13 November 2013

A three-miRNA signature as promising non-invasive diagnostic marker for gastric cancer.

scientific article

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Plasma miR-940 may serve as a novel biomarker for gastric cancer

scientific article published on 11 October 2015

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Breast cancer in Hong Kong, Southern China: the first population-based analysis of epidemiological characteristics, stage-specific, cancer-specific, and disease-free survival in breast cancer patients: 1997-2001.

scientific article

Clinical and pathological characteristics of Chinese patients with BRCA related breast cancer.

scientific article

Does the use of shared decision-making consultation behaviors increase treatment decision-making satisfaction among Chinese women facing decision for breast cancer surgery?

scientific article published on 28 November 2013

miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer.

scientific article

The acceptance and feasibility of breast cancer screening in the East

scientific article published on 27 August 2007

Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome

scientific article published on July 25, 2012

A BRCA2 founder mutation and seven novel deleterious BRCA mutations in southern Chinese women with breast and ovarian cancer

scientific article published on 08 April 2009

Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

scientific article published on 20 March 2019

Breast cancer in Chinese women younger than age 40: are they different from their older counterparts?

scientific article published on 01 December 2008

Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide

scientific article

The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in genetic diagnosis of familial breast cancer.

scientific article published on 9 June 2015

The evolution of supportive care needs trajectories in women with advanced breast cancer during the 12 months following diagnosis.

scientific article

BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis.

scientific article published on 28 December 2013

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

scientific article

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article

Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries.

scientific article

A novel de novo BRCA1 mutation in a Chinese woman with early onset breast cancer.

scientific article

Detection of Methylated Circulating DNA as Noninvasive Biomarkers for Breast Cancer Diagnosis

scientific article published on 24 March 2017

Germline RECQL mutations in high risk Chinese breast cancer patients.

scientific article published on 28 April 2016

Integrating molecular mechanisms and clinical evidence in the management of trastuzumab resistant or refractory HER-2⁺ metastatic breast cancer.

scientific article published on 21 October 2011

Current Status of the Management of Hereditary Breast and Ovarian Cancer in Asia: First Report by the Asian BRCA Consortium

scientific article published on 18 November 2015

Waiting to see the doctor: understanding appraisal and utilization components of consultation delay for new breast symptoms in Chinese women

scientific article published on August 26, 2011

Characterization of the pathogenic mechanism of a novel BRCA2 variant in a Chinese family

scientific article published on 27 July 2007

List of works by Ava Kwong

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

Association analysis identifies 65 new breast cancer risk loci

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Circulating microRNAs as specific biomarkers for breast cancer detection.

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2,251 patients.

Circulating cell-free miRNAs as biomarker for triple-negative breast cancer

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Comparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testing

Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer.

The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study.

Validation of the Chinese version of the short-form Supportive Care Needs Survey Questionnaire (SCNS-SF34-C).

MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells.

A three-miRNA signature as promising non-invasive diagnostic marker for gastric cancer.

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

Plasma miR-940 may serve as a novel biomarker for gastric cancer

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

Breast cancer in Hong Kong, Southern China: the first population-based analysis of epidemiological characteristics, stage-specific, cancer-specific, and disease-free survival in breast cancer patients: 1997-2001.

Clinical and pathological characteristics of Chinese patients with BRCA related breast cancer.

Does the use of shared decision-making consultation behaviors increase treatment decision-making satisfaction among Chinese women facing decision for breast cancer surgery?

miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer.

The acceptance and feasibility of breast cancer screening in the East

Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome

A BRCA2 founder mutation and seven novel deleterious BRCA mutations in southern Chinese women with breast and ovarian cancer

Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

Breast cancer in Chinese women younger than age 40: are they different from their older counterparts?

Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide

The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in genetic diagnosis of familial breast cancer.

The evolution of supportive care needs trajectories in women with advanced breast cancer during the 12 months following diagnosis.

BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis.

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries.

A novel de novo BRCA1 mutation in a Chinese woman with early onset breast cancer.

Detection of Methylated Circulating DNA as Noninvasive Biomarkers for Breast Cancer Diagnosis

Germline RECQL mutations in high risk Chinese breast cancer patients.

Integrating molecular mechanisms and clinical evidence in the management of trastuzumab resistant or refractory HER-2⁺ metastatic breast cancer.

Current Status of the Management of Hereditary Breast and Ovarian Cancer in Asia: First Report by the Asian BRCA Consortium

Waiting to see the doctor: understanding appraisal and utilization components of consultation delay for new breast symptoms in Chinese women

Characterization of the pathogenic mechanism of a novel BRCA2 variant in a Chinese family