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List of works by Hervé Dombret

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Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

scientific article
Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia

scientific article
Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study

scientific article
Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

scientific article
Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

scientific article published on March 2017
International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts

scientific article published on 18 May 2015
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study

scientific article
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

scientific article published on 17 March 2005
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence

scientific article
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

scientific article
Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia--results of the prospective multicenter LALA-94 trial

scientific article published in October 2002
A 17-gene stemness score for rapid determination of risk in acute leukaemia

scientific article published on 7 December 2016
The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children

scientific article published on 23 April 2007
Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study

scientific article
An update of current treatments for adult acute myeloid leukemia

scientific article published on December 10, 2015
Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience

scientific article
Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience

scientific article
Randomized study of intensified anthracycline doses for induction and recombinant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study

scientific article published on 4 January 2010
Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype

scientific article
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia

scientific article
Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group

scientific article published on 12 July 2010
Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

scientific article
Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia

scientific article published in September 2016
BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia

scientific article published on April 2006
Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia

scientific article published on 15 April 2015
NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

scientific article
Blinatumomab for minimal residual disease in adults with B-precursor acute lymphoblastic leukemia

scientific article
BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells

scientific article
Severe peripheral arterial disease during nilotinib therapy

scientific article
Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial

scientific article
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

scientific article
Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: a randomized, controlled trial

scientific article published on 30 March 2004
Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

scientific article
Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia

scientific article published in June 2003
Successful tyrosine kinase inhibitor therapy in a refractory B-cell precursor acute lymphoblastic leukemia with EBF1-PDGFRB fusion

scientific article published on November 2013
Is Cytarabine Useful in the Treatment of Acute Promyelocytic Leukemia? Results of a Randomized Trial From the European Acute Promyelocytic Leukemia Group

article by Lionel Adès et al published 20 December 2006 in Journal of Clinical Oncology
Treatment of newly diagnosed acute promyelocytic leukemia (APL): a comparison of French-Belgian-Swiss and PETHEMA results

scientific article
A randomized phase 3 study of tipifarnib compared with best supportive care, including hydroxyurea, in the treatment of newly diagnosed acute myeloid leukemia in patients 70 years or older

scientific article published on 21 May 2009
Dasatinib in imatinib-resistant or imatinib-intolerant chronic myeloid leukemia in blast phase after 2 years of follow-up in a phase 3 study: efficacy and tolerability of 140 milligrams once daily and 70 milligrams twice daily

scientific article published on August 2010
Role of allogeneic stem cell transplantation in adult patients with Ph-negative acute lymphoblastic leukemia

scientific article published on January 13, 2015
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup

scientific article
Phase II trial of arsenic trioxide and alpha interferon in patients with relapsed/refractory adult T-cell leukemia/lymphoma

scientific article published on January 2004
Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia

scientific article published on 06 October 2008
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome

scientific article
Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial

scientific article
l‐asparaginase loaded red blood cells in refractory or relapsing acute lymphoblastic leukaemia in children and adults: results of the GRASPALL 2005‐01 randomized trial

scientific article published on February 20, 2011
In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia

scientific article published in November 2002
Early onset hypercholesterolemia induced by the 2nd-generation tyrosine kinase inhibitor nilotinib in patients with chronic phase-chronic myeloid leukemia

scientific article
TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression

scientific article
Adverse prognostic significance of CD20 expression in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia

scientific article

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