List of works - Michele T M Hu

Association between early-onset Parkinson's disease and mutations in the parkin gene

scientific article (publication date: 25 May 2000)

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

scientific article

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

scientific article

A two-stage meta-analysis identifies several new loci for Parkinson's disease

scientific article

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

scientific article

Friedreich's ataxia: point mutations and clinical presentation of compound heterozygotes

scientific article

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

scientific article published on 17 February 2016

Functional connectivity in the basal ganglia network differentiates PD patients from controls

scientific article

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.

scientific article published on 28 August 2016

The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort

scientific article published on 12 October 2013

Dopamine enhances willingness to exert effort for reward in Parkinson's disease.

scientific article

REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease.

scientific article

Origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from Founder effects

scientific article published on 14 February 2001

Predictors of cognitive impairment in an early stage Parkinson's disease cohort

scientific article

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study

scientific article

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases

scientific article

Visual short-term memory deficits associated with GBA mutation and Parkinson's disease

scientific article

Identification of distinct circulating exosomes in Parkinson's disease

scientific article

Comprehensive morphometry of subcortical grey matter structures in early-stage Parkinson's disease

scientific article published on 16 July 2013

Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study

scientific article

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease

scientific article

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease

scientific article published on 12 June 2016

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson’s disease

scientific article

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

scientific article published on 29 November 2018

The alpha-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. European Consortium on Genetic Susceptibility in Parkinson's Disease

scientific article

Parkinson's Disease Subtypes in the Oxford Parkinson Disease Centre (OPDC) Discovery Cohort

scientific article published on June 2015

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

scientific article published on 01 March 2019

Prodromal Parkinsonism and Neurodegenerative Risk Stratification in REM Sleep Behavior Disorder.

scientific article published on 4 May 2017

Challenges in the reproducibility of clinical studies with resting state fMRI: An example in early Parkinson's disease.

scientific article

The Ile93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease

scientific article

Developing and validating Parkinson's disease subtypes and their motor and cognitive progression

scientific article published on 25 July 2018

Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease

scientific article (publication date: December 2004)

Use of human intravenous immunoglobulin in lower motor neuron syndromes

scientific article

Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis

scientific article published on 13 January 2018

Validation of conversion between mini-mental state examination and montreal cognitive assessment

scientific article

Antisaccades and executive dysfunction in early drug-naive Parkinson's disease: The discovery study.

scientific article published on 20 January 2015

Neuroimaging in pre-motor Parkinson's disease

scientific article

Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease

scientific article published on 9 April 2015

Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease

scientific article

Visual short-term memory deficits in REM sleep behaviour disorder mirror those in Parkinson's disease.

scientific article

How well do we recognise non-motor symptoms in a British Parkinson's disease population?

scientific article published on 11 March 2011

The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations

scientific article

Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned

scientific article

Delineating nonmotor symptoms in early Parkinson's disease and first-degree relatives

scientific article published on 14 July 2015

Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease--Report of the JPND Working Group BioLoC-PD.

scientific article published on 3 November 2015

PARK6 is a common cause of familial parkinsonism

scientific article

Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

scientific article

Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease

scientific article

Smartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls, and PD

scientific article published on 19 September 2018

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease

scientific article published on 24 January 2017

List of works by Michele T M Hu

Association between early-onset Parkinson's disease and mutations in the parkin gene

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

A two-stage meta-analysis identifies several new loci for Parkinson's disease

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Friedreich's ataxia: point mutations and clinical presentation of compound heterozygotes

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

Functional connectivity in the basal ganglia network differentiates PD patients from controls

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.

The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort

Dopamine enhances willingness to exert effort for reward in Parkinson's disease.

REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease.

Origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from Founder effects

Predictors of cognitive impairment in an early stage Parkinson's disease cohort

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases

Visual short-term memory deficits associated with GBA mutation and Parkinson's disease

Identification of distinct circulating exosomes in Parkinson's disease

Comprehensive morphometry of subcortical grey matter structures in early-stage Parkinson's disease

Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson’s disease

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

The alpha-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. European Consortium on Genetic Susceptibility in Parkinson's Disease

Parkinson's Disease Subtypes in the Oxford Parkinson Disease Centre (OPDC) Discovery Cohort

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

Prodromal Parkinsonism and Neurodegenerative Risk Stratification in REM Sleep Behavior Disorder.

Challenges in the reproducibility of clinical studies with resting state fMRI: An example in early Parkinson's disease.

The Ile93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease

Developing and validating Parkinson's disease subtypes and their motor and cognitive progression

Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease

Use of human intravenous immunoglobulin in lower motor neuron syndromes

Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis

Validation of conversion between mini-mental state examination and montreal cognitive assessment

Antisaccades and executive dysfunction in early drug-naive Parkinson's disease: The discovery study.

Neuroimaging in pre-motor Parkinson's disease

Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease

Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease

Visual short-term memory deficits in REM sleep behaviour disorder mirror those in Parkinson's disease.

How well do we recognise non-motor symptoms in a British Parkinson's disease population?

The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations

Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned

Delineating nonmotor symptoms in early Parkinson's disease and first-degree relatives

Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease--Report of the JPND Working Group BioLoC-PD.

PARK6 is a common cause of familial parkinsonism

Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease

Smartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls, and PD

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease