List of works - Daniel Pipeleers

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

scientific article

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells

scientific article

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

scientific article

Interleukin-6 regulates pancreatic alpha-cell mass expansion

scientific article

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

scientific article

Screening for insulitis in adult autoantibody-positive organ donors

scientific article

Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation

scientific article

Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft

scholarly article

Heterogeneity in Pancreatic β-cell Population

scientific article published on July 1, 1992

Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients

scientific article published on 14 July 2009

Beta-cell replication is increased in donor organs from young patients after prolonged life support

scientific article

Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells

scientific article

Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells

scientific article published on 17 March 2005

Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2beta) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease:

scientific article

Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport.

scientific article

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

scientific article published on 27 September 2006

Pancreatic beta cells in insulin-dependent diabetes

scientific article published on October 1, 1992

Islet Cell Surface Antibodies from Insulin-dependent Diabetics Bind Specifically to Pancreatic B Cells

scientific article published on July 1, 1982

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

scientific article published on 09 December 2009

Correlation between GABA release from rat islet beta-cells and their metabolic state

scientific article published in April 2002

Composition and function of macroencapsulated human embryonic stem cell-derived implants: comparison with clinical human islet cell grafts

scientific article

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming

scientific article

Contribution of postnatally formed small beta cell aggregates to functional beta cell mass in adult rat pancreas.

scientific article

Pancreatic duct cells in human islet cell preparations are a source of angiogenic cytokines interleukin-8 and vascular endothelial growth factor

scientific article published on 20 May 2008

Contribution of antibodies against IA-2β and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age.

scientific article

Beta cell count instead of beta cell mass to assess and localize growth in beta cell population following pancreatic duct ligation in mice

scientific article

Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase

scientific article

A view on beta cell transplantation in diabetes.

scientific article published in April 2002

Clusters of conserved beta cell marker genes for assessment of beta cell phenotype

scientific article

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.

scientific article

Protein markers for insulin-producing beta cells with higher glucose sensitivity

scientific article (publication date: 6 December 2010)

Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells

scientific article published on 01 April 1996

Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age.

scientific article published on January 2000

Glibenclamide treatment recruits beta-cell subpopulation into elevated and sustained basal insulin synthetic activity

scientific article published on January 2006

Effects of glucose and glucagon on the fructose 2,6-bisphosphate content of pancreatic islets and purified pancreatic B-cells. A comparison with isolated hepatocytes.

scientific article published on August 1984

Potential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivo

scientific journal article

Assessment of the role of interstitial glucagon in the acute glucose secretory responsiveness of in situ pancreatic beta-cells

scientific article published in March 2002

Comparison of cellular and medium insulin and GABA content as markers for living beta-cells

scientific article

Functional characteristics of neonatal rat β cells with distinct markers.

scientific article published on 19 December 2013

Glucose, regulator of survival and phenotype of pancreatic beta cells

scientific article published on January 2009

Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life

scientific journal article

Graves hyperthyroidism after stopping immunosuppressive therapy in type 1 diabetic Islet cell recipients with pretransplant TPO autoantibodies

scientific article published on 23 June 2009

Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function

scientific article published on 23 August 2013

Ectopic expression of E2F1 stimulates beta-cell proliferation and function.

scientific article

Predictors of progression to Type 1 diabetes: preparing for immune interventions in the preclinical disease phase

scientific article published on December 2013

Omentum is better site than kidney capsule for growth, differentiation, and vascularization of immature porcine β-cell implants in immunodeficient rats

scientific article published on December 2013

Functional beta-cell mass and insulin sensitivity is decreased in insulin-independent pancreas-kidney recipients

scientific article published on February 2009

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.

scientific article published on 12 July 2017

Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.

scientific article published on 27 March 2015

The beta cell population in type 1 diabetes.

scientific article published in January 2008

List of works by Daniel Pipeleers

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

Interleukin-6 regulates pancreatic alpha-cell mass expansion

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

Screening for insulitis in adult autoantibody-positive organ donors

Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation

Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft

Heterogeneity in Pancreatic β-cell Population

Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients

Beta-cell replication is increased in donor organs from young patients after prolonged life support

Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells

Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells

Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2beta) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease:

Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport.

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

Pancreatic beta cells in insulin-dependent diabetes

Islet Cell Surface Antibodies from Insulin-dependent Diabetics Bind Specifically to Pancreatic B Cells

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

Correlation between GABA release from rat islet beta-cells and their metabolic state

Composition and function of macroencapsulated human embryonic stem cell-derived implants: comparison with clinical human islet cell grafts

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming

Contribution of postnatally formed small beta cell aggregates to functional beta cell mass in adult rat pancreas.

Pancreatic duct cells in human islet cell preparations are a source of angiogenic cytokines interleukin-8 and vascular endothelial growth factor

Contribution of antibodies against IA-2β and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age.

Beta cell count instead of beta cell mass to assess and localize growth in beta cell population following pancreatic duct ligation in mice

Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase

A view on beta cell transplantation in diabetes.

Clusters of conserved beta cell marker genes for assessment of beta cell phenotype

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.

Protein markers for insulin-producing beta cells with higher glucose sensitivity

Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells

Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age.

Glibenclamide treatment recruits beta-cell subpopulation into elevated and sustained basal insulin synthetic activity

Effects of glucose and glucagon on the fructose 2,6-bisphosphate content of pancreatic islets and purified pancreatic B-cells. A comparison with isolated hepatocytes.

Potential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivo

Assessment of the role of interstitial glucagon in the acute glucose secretory responsiveness of in situ pancreatic beta-cells

Comparison of cellular and medium insulin and GABA content as markers for living beta-cells

Functional characteristics of neonatal rat β cells with distinct markers.

Glucose, regulator of survival and phenotype of pancreatic beta cells

Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life

Graves hyperthyroidism after stopping immunosuppressive therapy in type 1 diabetic Islet cell recipients with pretransplant TPO autoantibodies

Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function

Ectopic expression of E2F1 stimulates beta-cell proliferation and function.

Predictors of progression to Type 1 diabetes: preparing for immune interventions in the preclinical disease phase

Omentum is better site than kidney capsule for growth, differentiation, and vascularization of immature porcine β-cell implants in immunodeficient rats

Functional beta-cell mass and insulin sensitivity is decreased in insulin-independent pancreas-kidney recipients

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.

Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.

The beta cell population in type 1 diabetes.