List of works - Rupert Kaul

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

scientific article published on 10 November 2008

Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control

scientific article

HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

scientific article published in February 2000

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

scientific article

Sexual risk factors for HIV infection in early and advanced HIV epidemics in sub-Saharan Africa: systematic overview of 68 epidemiological studies

scientific article

Population-based surveillance for group A streptococcal necrotizing fasciitis: Clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases. Ontario Group A Streptococcal Study

scientific article published on July 1997

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

scientific article published on 12 June 2011

Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis

scientific article

Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group

scientific article published on 01 April 1999

Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial

scientific article published on June 2004

Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells

scientific article published in November 2000

Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

scientific article

Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract

scientific article published on March 2007

HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers

scientific article published in January 1999

Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses

scientific article

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

scientific article

CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects

scientific article

Hormonal contraception and the risk of HIV acquisition: an individual participant data meta-analysis

scientific article

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

scientific article published in August 2012

Levels of innate immune factors in genital fluids: association of alpha defensins and LL-37 with genital infections and increased HIV acquisition

scientific article published in January 2009

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

scientific article

Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate

article

The genital tract immune milieu: an important determinant of HIV susceptibility and secondary transmission.

scientific article

Cross-Clade HIV-1–Specific Neutralizing IgA in Mucosal and Systemic Compartments of HIV-1–Exposed, Persistently Seronegative Subjects

article

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection

scientific article published in March 2008

Clinical and immunogenetic correlates of abacavir hypersensitivity

scientific article published in June 2005

HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control

scientific article published on 2 June 2010

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

scientific article published in March 2011

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope

scientific article

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells

scientific article published on 24 June 2015

Prevalent herpes simplex virus type 2 infection is associated with altered vaginal flora and an increased susceptibility to multiple sexually transmitted infections

scientific article published on 25 October 2007

Quality and quantity: mucosal CD4+ T cells and HIV susceptibility

scientific article

Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation

scientific article published on 26 July 2013

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

scientific article published in September 2010

Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers

article

Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

scientific article

New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers

scientific article (publication date: November 2001)

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

scientific article published in May 2002

Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition

scientific article

HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

scientific article published on 16 September 2013

Recombination following superinfection by HIV-1.

scientific article published in January 2004

Persistent HIV RNA shedding in semen despite effective antiretroviral therapy

scientific article published on 01 September 2009

HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers

scientific article

HIV-1-specific cellular immune responses among HIV-1-resistant sex workers

scientific article published in December 2000

Sexually transmitted infections and vaginal douching in a population of female sex workers in Nairobi, Kenya

scientific article

Plasma from patients with severe invasive group A streptococcal infections treated with normal polyspecific IgG inhibits streptococcal superantigen-induced T cell proliferation and cytokine production

scientific article published on 01 April 1996

Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa

scientific article

HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers

scientific article

IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses.

scientific article

How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?

scientific article

List of works by Rupert Kaul

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control

HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

Sexual risk factors for HIV infection in early and advanced HIV epidemics in sub-Saharan Africa: systematic overview of 68 epidemiological studies

Population-based surveillance for group A streptococcal necrotizing fasciitis: Clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases. Ontario Group A Streptococcal Study

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis

Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group

Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial

Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells

Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract

HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers

Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects

Hormonal contraception and the risk of HIV acquisition: an individual participant data meta-analysis

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

Levels of innate immune factors in genital fluids: association of alpha defensins and LL-37 with genital infections and increased HIV acquisition

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate

The genital tract immune milieu: an important determinant of HIV susceptibility and secondary transmission.

Cross-Clade HIV-1–Specific Neutralizing IgA in Mucosal and Systemic Compartments of HIV-1–Exposed, Persistently Seronegative Subjects

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection

Clinical and immunogenetic correlates of abacavir hypersensitivity

HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells

Prevalent herpes simplex virus type 2 infection is associated with altered vaginal flora and an increased susceptibility to multiple sexually transmitted infections

Quality and quantity: mucosal CD4+ T cells and HIV susceptibility

Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers

Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition

HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

Recombination following superinfection by HIV-1.

Persistent HIV RNA shedding in semen despite effective antiretroviral therapy

HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers

HIV-1-specific cellular immune responses among HIV-1-resistant sex workers

Sexually transmitted infections and vaginal douching in a population of female sex workers in Nairobi, Kenya

Plasma from patients with severe invasive group A streptococcal infections treated with normal polyspecific IgG inhibits streptococcal superantigen-induced T cell proliferation and cytokine production

Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa

HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers

IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses.

How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?