List of works - Michael Goggins

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

scientific article

Detection of circulating tumor DNA in early- and late-stage human malignancies

scientific article (publication date: 19 February 2014)

Pancreatic Cancer

scholarly article

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

scientific article

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

scientific article

Detection and localization of surgically resectable cancers with a multi-analyte blood test.

scientific article published on 18 January 2018

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

scientific article

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

scientific article

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

scientific article

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

scientific article published on 5 January 2012

International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer

scientific article published on November 7, 2012

Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study

scientific article published on 6 May 2006

Detectable clonal mosaicism and its relationship to aging and cancer

journal article published in 2012

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

scientific article published on 8 December 2011

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

scientific article (publication date: April 2003)

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

scientific article

Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds

scientific article published on 01 April 2004

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.

scientific article

Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach

scientific article

Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma

scientific article

Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma

scientific article published on 01 January 2007

ATM mutations in patients with hereditary pancreatic cancer

scientific article published on 29 December 2011

Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.

scientific article

Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels

scientific article

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

scientific article

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

scientific article

Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

scientific article

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

scientific article

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

scientific article published on November 2002

SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

scientific article published on 01 August 2003

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

scientific article

The prevalence of BRCA2 mutations in familial pancreatic cancer

scientific article published on 01 February 2007

Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers

scientific article published on April 2004

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

scientific article published on July 2003

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

scientific article published on May 2004

Comprehensive Proteomic Analysis of Human Pancreatic Juice

article

MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls.

scientific article

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

scientific article

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

scientific article

Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.

scientific article published on September 2006

Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

scientific article

Serum diagnosis of pancreatic adenocarcinoma using surface-enhanced laser desorption and ionization mass spectrometry

scientific article

STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas

scientific article

Pancreatic cancer

journal article published in 2002

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

scientific article

Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9

scientific article published on 01 January 2006

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas

scientific article

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

scientific article

MicroRNA Alterations of Pancreatic Intraepithelial Neoplasias

scientific article published on November 23, 2011

Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients

scientific article published on December 2009

List of works by Michael Goggins

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Detection of circulating tumor DNA in early- and late-stage human malignancies

Pancreatic Cancer

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

Detection and localization of surgically resectable cancers with a multi-analyte blood test.

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer

Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study

Detectable clonal mosaicism and its relationship to aging and cancer

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.

Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach

Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma

Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma

ATM mutations in patients with hereditary pancreatic cancer

Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.

Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

The prevalence of BRCA2 mutations in familial pancreatic cancer

Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

Comprehensive Proteomic Analysis of Human Pancreatic Juice

MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls.

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.

Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

Serum diagnosis of pancreatic adenocarcinoma using surface-enhanced laser desorption and ionization mass spectrometry

STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas

Pancreatic cancer

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

MicroRNA Alterations of Pancreatic Intraepithelial Neoplasias

Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients