List of works - Fergus J. Couch

Genome-wide association study identifies novel breast cancer susceptibility loci

scientific article published on 28 June 2007

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality

scientific article

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

scientific article published on 10 February 2008

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

scientific article

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

scientific article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

scientific article published on March 1996

A common coding variant in CASP8 is associated with breast cancer risk

article

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

scientific article published on 29 March 2009

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

scientific article

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

scientific article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Gene-panel sequencing and the prediction of breast-cancer risk

scientific article

Breast-cancer risk in families with mutations in PALB2

scientific article

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

scientific article

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

scientific article

Association analysis identifies 65 new breast cancer risk loci

scientific article published on 23 October 2017

Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation

scientific article

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes

scientific article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2

scientific article

BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer

scientific article published on 01 May 1997

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer

scientific article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers

scientific article published on 01 November 2001

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

scientific article published on 30 October 2011

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

scientific article published on 04 August 2009

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families

scientific article published on November 1996

Two decades after BRCA: setting paradigms in personalized cancer care and prevention

scientific article

International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers

scientific article

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

scientific article published on 01 December 1994

ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

scientific article published on 3 November 2011

Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging

scientific article published on 27 July 2009

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

scientific article published on 16 October 2007

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

The prevalence of BRCA2 mutations in familial pancreatic cancer

scientific article published on 01 February 2007

Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia

article

BRCA2 germline mutations in male breast cancer cases and breast cancer families

scientific article published on 01 May 1996

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

scientific article published on January 1997

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

scientific article

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

scientific article published on 13 November 2007

Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

scientific article published on 13 April 2017

List of works by Fergus J. Couch

Genome-wide association study identifies novel breast cancer susceptibility loci

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

A common coding variant in CASP8 is associated with breast cancer risk

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Gene-panel sequencing and the prediction of breast-cancer risk

Breast-cancer risk in families with mutations in PALB2

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

Association analysis identifies 65 new breast cancer risk loci

Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2

BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer

Prediction of breast cancer risk based on profiling with common genetic variants

Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families

Two decades after BRCA: setting paradigms in personalized cancer care and prevention

International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

The prevalence of BRCA2 mutations in familial pancreatic cancer

Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia

BRCA2 germline mutations in male breast cancer cases and breast cancer families

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer