List of works - Thomas Grewal

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

scientific article published in September 2006

Annexins--modulators of EGF receptor signalling and trafficking

scientific article published on June 2009

Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

scientific article

Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis

scientific article

Interleukins in glioblastoma pathophysiology: implications for therapy.

scientific article published on February 2013

Functional implications of plasma membrane condensation for T cell activation

scientific article

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

scientific article published on 13 January 2017

Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.

scientific article

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

scientific article published on 6 September 2012

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

scientific article published in September 2005

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex

scientific article

Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.

scientific article published on 17 April 2014

Hydrophobic and basic domains target proteins to lipid droplets

scientific article

Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.

scientific article published on 12 February 2003

Annexin A6-Linking Ca(2+) signaling with cholesterol transport.

scientific article published on October 2010

High density lipoprotein-induced signaling of the MAPK pathway involves scavenger receptor type BI-mediated activation of Ras.

scientific article published on 7 March 2003

Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton.

scientific article

Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment

scientific article published on 01 October 2000

Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis

scientific article published on 04 January 2010

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function.

scientific article

Annexin A6 is an organizer of membrane microdomains to regulate receptor localization and signalling

scientific article published on 12 October 2011

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

scientific article

Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo.

scientific article

Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin

scientific journal article

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation

scientific article published on July 16, 2012

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells.

scientific article published on 19 April 2012

Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.

scientific article

Differential Regulation of RasGAPs in Cancer.

scientific article

Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi

scientific article

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells.

scientific article published on 4 August 2014

Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex.

scientific article published on December 2006

The -6.1-kilobase chicken lysozyme enhancer is a multifactorial complex containing several cell-type-specific elements.

scientific article published on May 1992

Annexins - scaffolds modulating PKC localization and signaling

scientific article published on 27 February 2014

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

scientific article published on 23 September 2005

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

scientific article

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes.

scientific article published on 04 February 2015

Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A gene.

scientific article published on May 2001

Annexins - insights from knockout mice.

scientific article published on 17 June 2016

Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

scientific article

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling

scientific article

Mapping quantitative trait loci associated with barley net blotch resistance

scientific article published on 11 December 2007

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells

scientific article

Annexin A6 in the liver: From the endocytic compartment to cellular physiology

scientific article published on 27 October 2016

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

scientific article published on 17 November 2015

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

scientific article

Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation

scientific article

Annexin A6 - a multifunctional scaffold in cell motility

scientific article published on 6 January 2017

Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).

scientific article published on April 2004

Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport

scientific article published on February 2012

Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations

scientific article published on 16 August 2011

List of works by Thomas Grewal

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

Annexins--modulators of EGF receptor signalling and trafficking

Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis

Interleukins in glioblastoma pathophysiology: implications for therapy.

Functional implications of plasma membrane condensation for T cell activation

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex

Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.

Hydrophobic and basic domains target proteins to lipid droplets

Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.

Annexin A6-Linking Ca(2+) signaling with cholesterol transport.

High density lipoprotein-induced signaling of the MAPK pathway involves scavenger receptor type BI-mediated activation of Ras.

Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton.

Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment

Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function.

Annexin A6 is an organizer of membrane microdomains to regulate receptor localization and signalling

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo.

Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells.

Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.

Differential Regulation of RasGAPs in Cancer.

Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells.

Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex.

The -6.1-kilobase chicken lysozyme enhancer is a multifactorial complex containing several cell-type-specific elements.

Annexins - scaffolds modulating PKC localization and signaling

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes.

Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A gene.

Annexins - insights from knockout mice.

Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling

Mapping quantitative trait loci associated with barley net blotch resistance

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells

Annexin A6 in the liver: From the endocytic compartment to cellular physiology

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation

Annexin A6 - a multifunctional scaffold in cell motility

Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).

Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport

Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations