List of works - Mauro Perretti

Resolution of inflammation: state of the art, definitions and terms

scientific article

Inflammatory resolution: new opportunities for drug discovery

scientific article published on May 2004

Annexin A1 and glucocorticoids as effectors of the resolution of inflammation

scientific article

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

scientific article

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

scientific article (publication date: November 2002)

Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse

scientific journal article

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

scientific article published on December 17, 2012

Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation

scientific article

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses.

scientific article published on 09 October 2013

Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions

scientific article

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

scientific article (publication date: July 2015)

Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects

scientific article

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles

scientific article published on 01 July 2008

Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.

scientific article published on 8 November 2005

Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.

scientific article

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

scientific article published on February 2015

Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration

scientific article published on 01 November 1996

Annexin-A1: a pivotal regulator of the innate and adaptive immune systems

scientific article published on 21 July 2008

Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10.

scientific article published in February 1999

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment.

scholarly article

Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1

scientific article published on November 1998

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

scientific article

Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors

scientific article published on 4 May 2006

Resolution of Inflammation: What Controls Its Onset?

scientific article

Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry.

scientific article

Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo

scientific article published on April 2010

Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing

scientific article

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

scientific article published in November 2015

Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.

scientific article published in March 2004

Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties

scientific article published on 08 May 2013

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis.

scientific article

Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model

scientific article published on January 1, 1998

Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26)

scientific article published on 01 March 2005

Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1.

scientific article published on March 1997

Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis.

scientific article

A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.

scientific article published on October 2003

Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics

scientific article published on October 2009

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.

scientific article

A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils.

scientific article

Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro

scientific article published on 6 July 2005

Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.

scientific article published in October 2001

Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo

scientific journal article

Annexin 1 and the biology of the neutrophil

scientific article published on 13 February 2004

Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation

scientific article published on 22 February 2007

Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1

scientific article published on 01 February 1993

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

scientific article published in October 2002

Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation.

scientific article published on June 2005

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair

scientific journal article

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

scientific article

Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.

scientific article

List of works by Mauro Perretti

Resolution of inflammation: state of the art, definitions and terms

Inflammatory resolution: new opportunities for drug discovery

Annexin A1 and glucocorticoids as effectors of the resolution of inflammation

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses.

Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles

Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.

Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration

Annexin-A1: a pivotal regulator of the innate and adaptive immune systems

Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10.

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment.

Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors

Resolution of Inflammation: What Controls Its Onset?

Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry.

Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo

Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.

Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis.

Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model

Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26)

Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1.

Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis.

A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.

Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.

A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils.

Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro

Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.

Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo

Annexin 1 and the biology of the neutrophil

Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation

Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation.

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.