List of works - Dermot McGovern

Analysis of protein-coding genetic variation in 60,706 humans

scientific article (publication date: 17 August 2016)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

scientific article

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

scientific article

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

scientific article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Disease-specific alterations in the enteric virome in inflammatory bowel disease

scientific article

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

scientific article

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

scientific article

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

scientific article

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

scientific article

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

scientific article published in May 2005

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

scientific article

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

scientific article

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

scientific article (publication date: 15 May 2002)

Genetics of Inflammatory Bowel Diseases

scientific article published on 06 August 2015

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

The IL23 axis plays a key role in the pathogenesis of IBD.

scientific article published on October 2007

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

scientific article

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

scientific article published on 21 December 2012

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci

scientific journal article

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism

scientific article

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

scientific article

A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease

scientific article

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

scientific article published on 29 May 2019

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

scientific article

Genetic predictors of medically refractory ulcerative colitis

scientific journal article

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease

scientific article

Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

scientific article

Review article: the genetics of inflammatory bowel disease

scientific article

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease

scientific article published on April 2003

Recent advances in IBD pathogenesis: genetics and immunobiology

scientific article published on December 2008

The efficacy of methotrexate for maintaining remission in inflammatory bowel disease

scientific article

Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium

scientific article

TUCAN (CARD8) genetic variants and inflammatory bowel disease.

scientific article

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

scientific article published in January 2018

IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein

scientific article

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

scientific article

Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease

scientific article published on June 2009

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

scientific article

Role ofNOD2 variants in spondylarthritis

scientific article published on 01 June 2002

The impact of preoperative serum anti-TNFα therapy levels on early postoperative outcomes in inflammatory bowel disease surgery

scientific article published on March 2015

CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi.

scientific article published in January 2018

Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

scientific article

A common CTLA4 haplotype associated with coeliac disease

scientific article published on 01 April 2005

Host–microbe relationships in inflammatory bowel disease detected by bacterial and metaproteomic analysis of the mucosal–luminal interface

scientific article published on June 22, 2011

List of works by Dermot McGovern

Analysis of protein-coding genetic variation in 60,706 humans

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

Common variants at five new loci associated with early-onset inflammatory bowel disease

Disease-specific alterations in the enteric virome in inflammatory bowel disease

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

Genetics of Inflammatory Bowel Diseases

Fine-mapping inflammatory bowel disease loci to single-variant resolution

The IL23 axis plays a key role in the pathogenesis of IBD.

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

Genetic predictors of medically refractory ulcerative colitis

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease

Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

Review article: the genetics of inflammatory bowel disease

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease

Recent advances in IBD pathogenesis: genetics and immunobiology

The efficacy of methotrexate for maintaining remission in inflammatory bowel disease

Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium

TUCAN (CARD8) genetic variants and inflammatory bowel disease.

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

Role ofNOD2 variants in spondylarthritis

The impact of preoperative serum anti-TNFα therapy levels on early postoperative outcomes in inflammatory bowel disease surgery

CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi.

Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

A common CTLA4 haplotype associated with coeliac disease

Host–microbe relationships in inflammatory bowel disease detected by bacterial and metaproteomic analysis of the mucosal–luminal interface