List of works - Petr Pecina

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.

scientific article published on 5 October 2005

The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: from respiration to apoptosis

journal article published in 2011

Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease.

scientific article published on 09 October 2008

Mitochondrial diseases and genetic defects of ATP synthase.

scientific article

Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1

scientific article

Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains

scientific article

Phosphomimetic substitution of cytochrome C tyrosine 48 decreases respiration and binding to cardiolipin and abolishes ability to trigger downstream caspase activation

scientific article published in August 2010

Evaluation of basic mitochondrial functions using rat tissue homogenates

scientific article published on 02 June 2011

A suggested role for mitochondria in Noonan syndrome.

scientific article published on 14 October 2009

Cytochrome C is tyrosine 97 phosphorylated by neuroprotective insulin treatment

scientific article

Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome

scientific article published in September 2003

Isolation of regulatory-competent, phosphorylated cytochrome C oxidase.

scientific article published in January 2009

Diminished synthesis of subunit a (ATP6) and altered function of ATP synthase and cytochrome c oxidase due to the mtDNA 2 bp microdeletion of TA at positions 9205 and 9206.

scientific article published on November 2004

Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy.

scientific article published on 20 November 2011

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

scientific article

Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations

scientific article published on 21 July 2004

Adaptation of respiratory chain biogenesis to cytochrome c oxidase deficiency caused by SURF1 gene mutations

scientific article published on 20 March 2012

Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride.

scientific article published on 19 April 2006

Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6.

scientific article published on 27 July 2016

Two components in pathogenic mechanism of mitochondrial ATPase deficiency: energy deprivation and ROS production.

scientific article

Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.

scientific article published on 12 January 2016

COX7AR is a Stress-inducible Mitochondrial COX Subunit that Promotes Breast Cancer Malignancy

scientific article published on 23 August 2016

Mitochondrial ATP synthasome: Expression and structural interaction of its components.

scientific article published on 10 July 2015

Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry

scientific article

High molecular weight forms of mammalian respiratory chain complex II

scientific article

Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production.

scientific article published on 9 August 2017

Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect

scientific article

Loss of COX4I1 Leads to Combined Respiratory Chain Deficiency and Impaired Mitochondrial Protein Synthesis

scientific article published in 2021

List of works by Petr Pecina

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.

The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: from respiration to apoptosis

Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease.

Mitochondrial diseases and genetic defects of ATP synthase.

Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1

Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains

Phosphomimetic substitution of cytochrome C tyrosine 48 decreases respiration and binding to cardiolipin and abolishes ability to trigger downstream caspase activation

Evaluation of basic mitochondrial functions using rat tissue homogenates

A suggested role for mitochondria in Noonan syndrome.

Cytochrome C is tyrosine 97 phosphorylated by neuroprotective insulin treatment

Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome

Isolation of regulatory-competent, phosphorylated cytochrome C oxidase.

Diminished synthesis of subunit a (ATP6) and altered function of ATP synthase and cytochrome c oxidase due to the mtDNA 2 bp microdeletion of TA at positions 9205 and 9206.

Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy.

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations

Adaptation of respiratory chain biogenesis to cytochrome c oxidase deficiency caused by SURF1 gene mutations

Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride.

Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6.

Two components in pathogenic mechanism of mitochondrial ATPase deficiency: energy deprivation and ROS production.

Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.

COX7AR is a Stress-inducible Mitochondrial COX Subunit that Promotes Breast Cancer Malignancy

Mitochondrial ATP synthasome: Expression and structural interaction of its components.

Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry

High molecular weight forms of mammalian respiratory chain complex II

Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production.

Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect

Loss of COX4I1 Leads to Combined Respiratory Chain Deficiency and Impaired Mitochondrial Protein Synthesis

Impaired mitochondrial energetic in patients harbouring SURF1 mutations is caused by uncoupling of cytochrome c oxidase