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List of works by Bram van der Eerden

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Systemic and local regulation of the growth plate.

scientific article published on December 2003
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5

scientific article
Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia.

scientific article published on 10 September 2016
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

scientific article
Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a

scientific article
Klotho prevents renal calcium loss.

scientific article published on 27 August 2009
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

scientific article
Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth

scientific article published on 01 June 2000
Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.

scientific article
1Alpha,25-(OH)2D3 acts in the early phase of osteoblast differentiation to enhance mineralization via accelerated production of mature matrix vesicles.

scientific article
Expression of estrogen receptor alpha and beta in the epiphyseal plate of the rat.

scientific article published in March 2002
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway

scientific article
An Age-Dependent Interaction with Leptin Unmasks Ghrelin's Bone-Protective Effects

scientific article published on June 14, 2012
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses.

scientific article
Sex steroid metabolism in the tibial growth plate of the rat

scientific article published on 01 October 2002
Gender differences in expression of androgen receptor in tibial growth plate and metaphyseal bone of the rat

scientific article published on 01 June 2002
Bone resorption inhibitor alendronate normalizes the reduced bone thickness of TRPV5(-/-) mice.

scientific article published in November 2008
The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.

scientific article
1α,25-dihydroxyvitamin D3 stimulates activin A production to fine-tune osteoblast-induced mineralization.

scientific article published on November 2013
TRPV4 deficiency causes sexual dimorphism in bone metabolism and osteoporotic fracture risk.

scientific article published on 29 September 2013
Unraveling the human bone microenvironment beyond the classical extracellular matrix proteins: a human bone protein library.

scientific article
MicroRNAs in the skeleton: cell-restricted or potent intercellular communicators?

scientific article published on 14 May 2014
Ghrelin and bone.

scientific article published on January 2008
Serum Phosphate Is Associated With Fracture Risk: The Rotterdam Study and MrOS.

scientific article published on 8 February 2017
IFNβ impairs extracellular matrix formation leading to inhibition of mineralization by effects in the early stage of human osteoblast differentiation.

scientific article
Using the Connectivity Map to discover compounds influencing human osteoblast differentiation.

scientific article published in December 2017
Evidence of vitamin D and interferon‐β cross‐talk in human osteoblasts with 1α,25‐dihydroxyvitamin D3 being dominant over interferon‐β in stimulating mineralization

scientific article published on September 1, 2012
Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice

scientific article (publication date: 2012)
Thrombin receptor deficiency leads to a high bone mass phenotype by decreasing the RANKL/OPG ratio

scientific article published on 18 November 2014
Meeting report of the 2016 bone marrow adiposity meeting.

scientific article published on 05 April 2017
Characterization of vitamin D-deficient klotho(-/-) mice: do increased levels of serum 1,25(OH)2D3 cause disturbed calcium and phosphate homeostasis in klotho(-/-) mice?

scientific article published on 09 July 2012
Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling

scientific article published on 25 July 2014
Comparative proteomic profiling of human osteoblast-derived extracellular matrices identifies proteins involved in mesenchymal stromal cell osteogenic differentiation and mineralization

scientific article published on 8 March 2017
Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells

scientific article published on 02 September 2016
Immunotherapy Added to Antibiotic Treatment Reduces Relapse of Disease in a Mouse Model of Tuberculosis.

scientific article published on 21 September 2016
Effects of Chronic Estrogen Administration in the Ventromedial Nucleus of the Hypothalamus (VMH) on Fat and Bone Metabolism in Ovariectomized Rats

scientific article published on 24 October 2016
Evidence for genomic and nongenomic actions of estrogen in growth plate regulation in female and male rats at the onset of sexual maturation.

scientific article published in November 2002
Osteoclastogenic capacity of peripheral blood mononuclear cells is not different between women with and without osteoporosis.

scientific article published on 11 November 2016
A human vitamin D receptor mutation causes rickets and impaired Th1/Th17 responses

scientific article published on 6 September 2014
Hydroxychloroquine affects bone resorption both in vitro and in vivo.

scientific article published on 30 May 2017
Bone, a dynamic and integrating tissue.

scientific article published on 23 August 2014
Adverse Effects of Diabetes Mellitus on the Skeleton of Aging Mice

scientific article published on 18 September 2015
The vitamin D analog ZK191784 normalizes decreased bone matrix mineralization in mice lacking the calcium channel TRPV5.

scientific article published in February 2013
Identification of microRNAs in Human Plasma

scientific article published on 01 January 2015
Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro.

scientific article
Effect of x-irradiation on growth and the expression of parathyroid hormone-related peptide and Indian hedgehog in the tibial growth plate of the rat

scientific article published on 01 January 2003
A soluble activin type IIA receptor mitigates the loss of femoral neck bone strength and cancellous bone mass in a mouse model of disuse osteopenia

scientific article published on 28 February 2018
Zika virus alters osteogenic lineage progression of human mesenchymal stromal cells

scientific article published in 2022
Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism.

scientific article published on 18 April 2016
Extracellular Vesicles Derived From Adult and Fetal Bone Marrow Mesenchymal Stromal Cells Differentially Promote <i>ex vivo</i> Expansion of Hematopoietic Stem and Progenitor Cells

scientific article published on 25 February 2021

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