List of works - Jan-Åke Gustafsson

Estrogen signaling: a subtle balance between ER alpha and ER beta

scientific article published on August 2003

Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

scholarly article

International Union of Pharmacology. LXIV. Estrogen receptors

scientific article

An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice

scholarly article

Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells

scientific article

Reflections on the discovery and significance of estrogen receptor beta

scientific article (publication date: May 2005)

An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth

scientific article

Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity

scientific article

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

scientific article

Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.

scientific article published on October 2005

Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain

scientific article

The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism

scientific article (publication date: 20 June 2003)

Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha

scholarly article

Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts

scientific article published on December 2006

Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation

scientific article (publication date: October 2003)

Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

scientific article

Role of estrogen receptor beta in colonic epithelium

scholarly article

Estrogen receptor beta: an overview and update

scientific article

A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia

scholarly article

Regulation of postnatal lung development and homeostasis by estrogen receptor beta.

scientific article published on December 2003

Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells

scientific article published on 14 July 2009

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

scientific article

LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

scientific article published on 13 April 2005

Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate

scientific journal article

Accumulation of foam cells in liver X receptor-deficient mice

scientific article published in August 2002

Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium

scientific article

Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice

scientific article published on 12 August 2008

Estrogen receptor (ER) beta modulates ERalpha-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters

scientific article published on 17 November 2005

Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.

scientific article published on 20 April 2006

Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters

scientific article

Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation

scientific article published on October 2003

Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells

scientific article published on April 2007

Transcriptional corepression by SHP: molecular mechanisms and physiological consequences

scientific article

Liver X Receptors as Insulin-mediating Factors in Fatty Acid and Cholesterol Biosynthesis

scientific article published on January 7, 2002

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

scientific article

Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death

scientific article

Cloning, expression, and characterization of a novel Escherichia coli thioredoxin

scientific article published in December 1997

Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice

scientific article (publication date: 8 March 2005)

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

scientific article published on 23 January 2009

Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia

scholarly article

Estrogen receptor and aryl hydrocarbon receptor signaling pathways

scientific article

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha

scientific article published on 11 September 2003

Genome-wide identification of estrogen receptor alpha-binding sites in mouse liver

scientific article

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

scientific article published on 11 February 2013

Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue

scientific article

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

scientific article

Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer

scientific article published in September 2004

Estrogen receptor beta in breast cancer--diagnostic and therapeutic implications

scientific article published on 04 March 2009

Dragon ERE Finder version 2: A tool for accurate detection and analysis of estrogen response elements in vertebrate genomes

scientific article

On the role of liver X receptors in lipid accumulation in adipocytes

scientific article published on February 2003

List of works by Jan-Åke Gustafsson

Estrogen signaling: a subtle balance between ER alpha and ER beta

Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

International Union of Pharmacology. LXIV. Estrogen receptors

An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice

Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells

Reflections on the discovery and significance of estrogen receptor beta

An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth

Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.

Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain

The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism

Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha

Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts

Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation

Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

Role of estrogen receptor beta in colonic epithelium

Estrogen receptor beta: an overview and update

A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia

Regulation of postnatal lung development and homeostasis by estrogen receptor beta.

Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate

Accumulation of foam cells in liver X receptor-deficient mice

Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium

Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice

Estrogen receptor (ER) beta modulates ERalpha-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters

Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.

Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters

Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation

Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells

Transcriptional corepression by SHP: molecular mechanisms and physiological consequences

Liver X Receptors as Insulin-mediating Factors in Fatty Acid and Cholesterol Biosynthesis

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death

Cloning, expression, and characterization of a novel Escherichia coli thioredoxin

Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia

Estrogen receptor and aryl hydrocarbon receptor signaling pathways

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha

Genome-wide identification of estrogen receptor alpha-binding sites in mouse liver

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer

Estrogen receptor beta in breast cancer--diagnostic and therapeutic implications

Dragon ERE Finder version 2: A tool for accurate detection and analysis of estrogen response elements in vertebrate genomes

On the role of liver X receptors in lipid accumulation in adipocytes