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List of works by Ana Cristina Rego

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Mechanisms of neurodegeneration in Huntington's disease.

scientific article published on June 2008
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases

scientific article published on October 1, 2003
Multiple Defects in Energy Metabolism in Alzheimers Disease

scientific article published on October 1, 2010
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

scientific article published on January 2009
Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

scientific article
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

scientific article published on 27 March 2008
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.

scientific article
Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors.

scientific article published on 22 August 2013
Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

scientific article
Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

scientific article
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

scientific article published in October 2006
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

scientific article published on 6 April 2015
Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease--resemblance to the effect of amphetamine drugs of abuse.

scientific article published on 25 August 2012
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

scientific article
Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells

scientific article
Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.

scientific article
Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

scientific article published on 14 July 2008
Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

scientific article
IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.

scientific article published on 18 December 2013
Antioxidant effect of flavonoids after ascorbate/Fe(2+)-induced oxidative stress in cultured retinal cells.

scientific article published in July 2001
Mitochondrial-Associated Metabolic Changes and Neurodegeneration in Huntingtons Disease - from Clinical Features to the Bench

scientific article published on October 1, 2010
Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.

scientific article published on 14 September 2012
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

scientific article
Bioenergetic dysfunction in Huntington's disease human cybrids.

scientific article published on 13 June 2011
Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress.

scientific article published on January 2013
Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

scientific article published on January 2005
Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

scientific article published on 6 September 2014
Mitochondrial Dysfunction in Huntington's Disease

scientific article published in January 2018
Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.

scientific article published on 20 May 2014
Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.

scientific article
Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress

scientific article published on 01 June 1999
Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

scientific article published on 24 March 2017
Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells--protective effect of cystamine and creatine

scientific article published on 5 September 2013
BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.

scientific article published on 23 June 2009
Sirtuins: double players in Huntington's disease

scientific article
OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration.

scientific article published on 11 December 2014
Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin.

scientific article published on 03 February 2016
Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells

scientific article published on 01 February 2000
Dual Effect of Lipid Peroxidation on the Membrane Order of Retinal Cells in Culture

article
IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

scientific article
Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.

scientific article published on 23 May 2013
Compromised mitochondrial complex II in models of Machado-Joseph disease.

scientific article
Adenosine modulation of d-[3H]aspartate release in cultured retina cells exposed to oxidative stress

scientific article published on 01 March 2000
Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

scientific article
Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.

scientific article published in May 2006
Adenosine Triphosphate Degradation Products After Oxidative Stress and Metabolic Dysfunction in Cultured Retinal Cells

scientific article published on 01 September 1997
FK506 ameliorates cell death features in Huntington's disease striatal cell models.

scientific article published on 15 June 2011
BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

scientific article published in July 2009
Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells

scientific article published on 16 July 2016
Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

scientific article published on 13 August 2014

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