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List of works by Joseph Makhema

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Prevention of HIV-1 infection with early antiretroviral therapy

scientific article
Antiretroviral Therapy for the Prevention of HIV-1 Transmission

scientific article published on 18 July 2016
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial

scientific article
Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana

scientific article
Response to antiretroviral therapy after a single, peripartum dose of nevirapine

scientific article
Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study

scientific article published on August 2006
Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana

scientific article
Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trial

scientific article
Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial

scientific article
Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey

scientific article published on 24 March 2016
Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana

scientific article published on 09 July 2007
Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy

scientific article
Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial

scientific article published on 11 October 2011
Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study

scientific article
Undisclosed Antiretroviral Drug Use in a Multinational Clinical Trial (HIV Prevention Trials Network 052)

scientific article published on November 15, 2013
Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial

scientific article
Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana

scientific article
Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection

scientific article published on July 2011
Effect of micronutrient supplementation on disease progression in asymptomatic, antiretroviral-naive, HIV-infected adults in Botswana: a randomized clinical trial

scientific article
Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana

scientific article
Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article
Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial

scientific article
HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission

scientific article
Pregnancy rates and birth outcomes among women on efavirenz-containing highly active antiretroviral therapy in Botswana

scientific article
Neural-Tube Defects and Antiretroviral Treatment Regimens in Botswana

scientific article published on 22 July 2019
Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy

scientific article published on 07 August 2017
Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study

scientific article published on 04 June 2018
Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana

scientific article published on 12 September 2015
Acceptability of infant male circumcision as part of HIV prevention and male reproductive health efforts in Gaborone, Botswana, and surrounding areas

scientific article
Evolution of proviral gp120 over the first year of HIV-1 subtype C infection

scientific article
Minor resistant variants in nevirapine-exposed infants may predict virologic failure on nevirapine-containing ART.

scientific article
Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection.

scientific article published on January 2009
Point-of-Care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities Is Feasible and Reliable

scientific article published on 12 October 2016
Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial

scientific article published on 09 May 2013
A randomized trial of Mogen clamp versus Plastibell for neonatal male circumcision in Botswana

scientific article published on April 2013
Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection

scientific article
HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana

scientific article published on July 2013
Increased risk of severe infant anemia after exposure to maternal HAART, Botswana

scientific article
Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana

scientific article published on 01 July 2019
Prevalence of human papillomavirus genotypes and associated cervical squamous intraepithelial lesions in HIV-infected women in Botswana

scientific article
Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana

scientific article
In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana

scientific article
Risk factors for very preterm delivery and delivery of very‐small‐for‐gestational‐age infants among HIV‐exposed and HIV‐unexposed infants in Botswana

scientific article published on July 20, 2011
Herpes simplex virus type 2 suppressive therapy with acyclovir or valacyclovir does not select for specific HIV-1 resistance in HIV-1/HSV-2 dually infected persons

scientific article
High Prevalence of Hypertension and Placental Insufficiency, but No In Utero HIV Transmission, among Women on HAART with Stillbirths in Botswana

scientific article published on February 22, 2012
Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana

scientific article
Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C.

scientific article published on 3 September 2012
Strengthening healthcare capacity through a responsive, country-specific, training standard: the KITSO AIDS training program's support of Botswana's national antiretroviral therapy rollout

scientific article published on 29 February 2008
Unintended pregnancy, contraceptive use, and childbearing desires among HIV-infected and HIV-uninfected women in Botswana: across-sectional study

scientific article published on 16 January 2016
Risk factors for early and late transmission of HIV via breast-feeding among infants born to HIV-infected women in a randomized clinical trial in Botswana

scientific article published on February 2009

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