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List of works by C. Ryan Miller

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An animal model of MYC-driven medulloblastoma

scientific article published on February 2012
Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy.

scientific article published on 13 November 2006
Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation

scientific article (publication date: 2012)
ClearCode34: A prognostic risk predictor for localized clear cell renal cell carcinoma

scientific article
HIF1α and HIF2α independently activate SRC to promote melanoma metastases

scientific article
Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.

scientific article published in December 2006
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.

scientific article
LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma

scientific article published on June 2012
Tryptase staining of mast cells may differentiate eosinophilic esophagitis from gastroesophageal reflux disease

scientific article published on October 26, 2010
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer.

scientific article
Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.

scientific article published on 29 April 2008
Gene expression profiling of gliomas: merging genomic and histopathological classification for personalised therapy.

scientific article
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

scientific article published on 23 January 2013
Diagnostic Utility of Major Basic Protein, Eotaxin-3, and Leukotriene Enzyme Staining in Eosinophilic Esophagitis

scientific article published on July 10, 2012
Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process

scientific article
αB-crystallin: a novel regulator of breast cancer metastasis to the brain

scientific article
Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases

scientific article published on January 1, 2011
Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

scientific article published on 02 January 2014
Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma.

scientific article
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.

scientific article published on 13 June 2016
Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models

scientific article
Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization.

scientific article
Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer.

scientific article
Evolutionary etiology of high-grade astrocytomas

scientific article published on October 10, 2013
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation

scientific article published on May 2017
Gray zones in brain tumor classification: evolving concepts.

scientific article published on September 2008
Risk of recurrence of resected stage I non-small cell lung cancer in elderly patients as compared with younger patients.

scientific article published in November 2009
High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma.

scientific article published on 09 September 2011
Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer

scientific article
The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.

scientific article
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

scientific article published on 28 January 2016
Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis.

scientific article
Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers

scientific article published on October 2008
Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.

scientific article published on 04 December 2013
Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.

scientific article published in February 2017
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.

scientific article published on 13 March 2018
Genetically engineered mouse models of diffuse gliomas

scientific article published on June 13, 2011
Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models

scientific article published on 13 January 2016
Contemporary murine models in preclinical astrocytoma drug development

scientific article
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.

scientific article published on 30 March 2017
LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases

scientific article published on 25 June 2018
MerTK as a therapeutic target in glioblastoma.

scientific article published on 12 June 2017
Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice

scientific article published on 12 August 2014
Hematopoietic Stem cell transplantation and lentiviral vector-based gene therapy for Krabbe's disease: Present convictions and future prospects.

scientific article
Tryptophan Metabolism Contributes to Radiation-Induced Immune Checkpoint Reactivation in Glioblastoma.

scientific article
Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.

scientific article
Development of DNA damage response signaling biomarkers using automated, quantitative image analysis

scientific article published on 05 December 2013
PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition

scientific article published in PLoS ONE
ASC deficiency suppresses proliferation and prevents medulloblastoma incidence

scientific article published on 27 January 2014
Markers of tyrosine kinase activity in eosinophilic esophagitis: a pilot study of the FIP1L1-PDGFRα fusion gene, pERK 1/2, and pSTAT5

scientific article published on August 5, 2011

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