List of works - Sean M. Davidson

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

scientific article

Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury

scientific article published on 26 April 2010

De novo cardiomyocytes from within the activated adult heart after injury

scientific article

Endothelial mitochondria: contributing to vascular function and disease

scientific article published on April 2007

Molecular regulation of cardiac hypertrophy

scientific article published on 26 February 2008

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

scientific article published on 23 February 2015

Plasma exosomes protect the myocardium from ischemia-reperfusion injury.

scientific article published in April 2015

Necrostatin: a potentially novel cardioprotective agent?

scientific article published on 31 July 2007

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

scientific article

Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore

scientific article

Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

scientific article published on 5 November 2003

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

scientific article

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening

scientific article

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

scientific article

Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

scientific article

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

scientific article published on 07 April 2016

Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection

scientific article published on 21 October 2005

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

scientific article

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury

scientific article published on 18 March 2011

Remote ischaemic preconditioning involves signalling through the SDF-1α/CXCR4 signalling axis

scientific article published on 6 August 2013

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

scientific article

Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse

scientific article published on 26 June 2008

Exosomes: nanoparticles involved in cardioprotection?

scientific article published on January 2014

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

scientific article published on 13 August 2007

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.

scientific article

Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction

scientific article

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

scientific article

The novel adipocytokine visfatin exerts direct cardioprotective effects

scientific article

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

scientific article published on 17 August 2018

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

scientific article

HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

scientific article published on 25 July 2014

Hsp25 and the p38 MAPK pathway are involved in differentiation of cardiomyocytes.

scientific article

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors

scientific journal article

Endothelial mitochondria and heart disease

scientific article published on 16 June 2010

Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop

scientific article

Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.

scientific article

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning

scientific article

9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection

scientific article

Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation

scientific article published on 23 December 2011

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

scientific article

Calcium microdomains and oxidative stress

scientific article published on 17 October 2006

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

scientific article

Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium.

scientific article published on April 2014

Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning

scientific article published on 23 June 2016

Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure

scientific article

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

scientific article published on 01 January 2019

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

scientific article

Exosomes and Cardiovascular Protection.

scientific article published on 29 October 2016

Novel therapeutic strategies for cardioprotection.

scientific article published on 13 May 2014

List of works by Sean M. Davidson

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury

De novo cardiomyocytes from within the activated adult heart after injury

Endothelial mitochondria: contributing to vascular function and disease

Molecular regulation of cardiac hypertrophy

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

Plasma exosomes protect the myocardium from ischemia-reperfusion injury.

Necrostatin: a potentially novel cardioprotective agent?

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore

Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury

Remote ischaemic preconditioning involves signalling through the SDF-1α/CXCR4 signalling axis

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse

Exosomes: nanoparticles involved in cardioprotection?

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.

Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

The novel adipocytokine visfatin exerts direct cardioprotective effects

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

Hsp25 and the p38 MAPK pathway are involved in differentiation of cardiomyocytes.

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors

Endothelial mitochondria and heart disease

Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop

Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning

9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection

Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

Calcium microdomains and oxidative stress

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium.

Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning

Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

Exosomes and Cardiovascular Protection.

Novel therapeutic strategies for cardioprotection.