List of works - Takashi Takahashi

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

scientific article

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

scientific article

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

scientific article

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

scientific article published in December 2004

Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence

scientific article

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

scientific article published in February 2005

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

scientific article

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

scientific article (publication date: 6 December 2011)

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

scientific article published on June 2005

Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster

scientific article

MicroRNAs in biological processes and carcinogenesis.

scientific article published on 6 October 2006

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

scientific article published on 20 March 2006

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

scientific article

let-7 regulates Dicer expression and constitutes a negative feedback loop

scientific article

Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis.

scientific article

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

article

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.

scientific article

let-7 and miR-17-92: small-sized major players in lung cancer development

scientific article

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

scientific article (publication date: July 2007)

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

scientific article published on July 2002

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation

scientific article published on August 1, 1992

Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction.

scientific article published on March 2004

Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.

scientific article

A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer.

scientific article published on July 2006

NKX2-1/TTF-1: An Enigmatic Oncogene that Functions as a Double-Edged Sword for Cancer Cell Survival and Progression

scientific article published on June 10, 2013

miR-375 is activated by ASH1 and inhibits YAP1 in a lineage-dependent manner in lung cancer.

scientific article

Differential inactivation of caspase-8 in lung cancers.

scientific article published on January 2002

Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.

scientific article published on 11 April 2007

Epidermal growth factor receptor gene amplification is acquired in association with tumor progression of EGFR-mutated lung cancer.

scientific article published in April 2008

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

scientific article (publication date: 4 April 2002)

Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers

scientific article

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells.

scientific article published on 11 November 2010

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer.

scientific article

Differential expression of the c-kit proto-oncogene in germ cell tumours.

scientific article

Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis.

scientific article

ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

scientific article published on December 2005

Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis

scientific article

Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis.

scientific article published on 22 June 2010

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

scientific article

Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer.

scientific article

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins

scientific article published in August 1992

A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer.

scientific article published in June 2007

Disproportionate representation ofKRAS gene mutation in atypical adenomatous hyperplasia, but even distribution ofEGFR gene mutation from preinvasive to invasive adenocarcinomas

article

K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

scientific article published on January 2004

Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer

scientific article

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo

scientific article published on 13 July 2012

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia

scientific article published on February 1992

Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis

scientific article

hDREF regulates cell proliferation and expression of ribosomal protein genes

scientific article

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma.

scientific article published on 11 January 2010

List of works by Takashi Takahashi

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster

MicroRNAs in biological processes and carcinogenesis.

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

let-7 regulates Dicer expression and constitutes a negative feedback loop

Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis.

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.

let-7 and miR-17-92: small-sized major players in lung cancer development

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation

Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction.

Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.

A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer.

NKX2-1/TTF-1: An Enigmatic Oncogene that Functions as a Double-Edged Sword for Cancer Cell Survival and Progression

miR-375 is activated by ASH1 and inhibits YAP1 in a lineage-dependent manner in lung cancer.

Differential inactivation of caspase-8 in lung cancers.

Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.

Epidermal growth factor receptor gene amplification is acquired in association with tumor progression of EGFR-mutated lung cancer.

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells.

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer.

Differential expression of the c-kit proto-oncogene in germ cell tumours.

Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis.

ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis

Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis.

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer.

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins

A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer.

Disproportionate representation ofKRAS gene mutation in atypical adenomatous hyperplasia, but even distribution ofEGFR gene mutation from preinvasive to invasive adenocarcinomas

K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia

Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis

hDREF regulates cell proliferation and expression of ribosomal protein genes

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma.