List of works - Sergey Mikhailov

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

scientific article published on 12 March 2009

Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.

scientific article

Detection of RNA hybridization by pyrene-labeled probes.

scientific article published in May 2009

DNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction- modification enzymes.

scientific article published on August 1997

Disaccharide pyrimidine nucleosides and their derivatives: a novel group of cell-penetrating inhibitors of poly(ADP-ribose) polymerase 1.

scientific article published on January 2013

Solid-supported 2'-O-glycoconjugation of oligonucleotides by azidation and click reactions

scientific article published on 10 May 2011

Synthesis of RNA ContainingO-β-D-Ribofuranosyl-(1″2′)-adenosine-5″-phosphate and 1-Methyladenosine, Minor Components of tRNA

scientific article published on 01 September 2005

Mapping of T7 RNA polymerase active site with novel reagents - oligonucleotides with reactive dialdehyde groups

article

Substrate specificity of Escherichia coli thymidine phosphorylase.

scientific article published in January 2007

Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine

scientific article published in April 2003

Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy

scientific article published on 01 December 2018

Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis.

scientific article published in January 2004

A route to 2',5'-oligoadenylates with increased stability towards phosphodiesterases.

scientific article published on August 1988

Chemical modification of the plant isoprenoid cytokinin N(6)-isopentenyladenosine yields a selective inhibitor of human enterovirus 71 replication

scientific article published on 25 November 2014

Disaccharide nucleosides and oligonucleotides on their basis. New tools for the study of enzymes of nucleic acid metabolism.

scientific article

Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate

scientific article published in May 2003

Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside

scientific article

Fluorination of Naturally Occurring N⁶-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity.

scientific article

Affinity modification of EcoRII DNA methyltransferase by the dialdehyde-substituted DNA duplexes: mapping the enzyme region that interacts with DNA.

scientific article

N⁶-(benzyloxymethyl)adenosine is a novel anticytokinin, an antagonist of cytokinin receptor CRE1/AHK4 of Arabidopsis.

scientific article

Substrate specificity of thymidine phosphorylase of E. coli: role of hydroxyl groups.

scientific article

2'-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides

scientific article published on January 2007

Facile synthesis of 8-azido-6-benzylaminopurine

scientific article published on 01 July 2011

Oligodeoxynucleotides containing N1-methyl-2'-deoxyadenosine and N6-methyl-2'-deoxyadenosine

scientific article published in September 2009

Chemoenzymatic synthesis of cytokinins from nucleosides: ribose as a blocking group

scientific article published on 9 March 2018

Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.

scientific article published in May 2003

Oligonucleotides Containing Disaccharide Nucleosides: Synthesis, Physicochemical, and Substrate Properties

scientific article published on 01 May 2003

A comparative study on the cleavage of stereoisomeric uridylyl(3',5')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts.

scientific article published in August 2002

Substrate properties of C'-methyl UTP derivatives in T7 RNA polymerase reactions. Evidence for N-type NTP conformation

scientific article published on 01 January 1997

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases

scientific article published on 05 April 2020

Incorporation of a disaccharide nucleoside into the backbone of double-stranded DNA: crystallization and preliminary X-ray diffraction

scientific article published on 30 September 2005

Determination of the nucleotide conformation in the productive enzyme-substrate complexes of RNA-depolymerases

scientific article published on 01 March 1997

Chemical incorporation of 1-methyladenosine, minor tRNA component, into oligonucleotides.

scientific article published in May 2003

Distinct Peculiarities of In Planta Synthesis of Isoprenoid and Aromatic Cytokinins

scientific article published on 05 January 2020

Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine

scientific article published on May 2003

Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine Nucleosides

scientific article published on 13 August 2020

Physicochemical characterization of uridine phosphorylase from Shewanella oneidensis MR-1

scientific article published on 01 July 2013

List of works by Sergey Mikhailov

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.

Detection of RNA hybridization by pyrene-labeled probes.

DNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction- modification enzymes.

Disaccharide pyrimidine nucleosides and their derivatives: a novel group of cell-penetrating inhibitors of poly(ADP-ribose) polymerase 1.

Solid-supported 2'-O-glycoconjugation of oligonucleotides by azidation and click reactions

Synthesis of RNA ContainingO-β-D-Ribofuranosyl-(1″2′)-adenosine-5″-phosphate and 1-Methyladenosine, Minor Components of tRNA

Mapping of T7 RNA polymerase active site with novel reagents - oligonucleotides with reactive dialdehyde groups

Substrate specificity of Escherichia coli thymidine phosphorylase.

Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine

Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy

Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis.

A route to 2',5'-oligoadenylates with increased stability towards phosphodiesterases.

Chemical modification of the plant isoprenoid cytokinin N(6)-isopentenyladenosine yields a selective inhibitor of human enterovirus 71 replication

Disaccharide nucleosides and oligonucleotides on their basis. New tools for the study of enzymes of nucleic acid metabolism.

Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate

Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside

Fluorination of Naturally Occurring N⁶-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity.

Affinity modification of EcoRII DNA methyltransferase by the dialdehyde-substituted DNA duplexes: mapping the enzyme region that interacts with DNA.

N⁶-(benzyloxymethyl)adenosine is a novel anticytokinin, an antagonist of cytokinin receptor CRE1/AHK4 of Arabidopsis.

Substrate specificity of thymidine phosphorylase of E. coli: role of hydroxyl groups.

2'-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides

Facile synthesis of 8-azido-6-benzylaminopurine

Oligodeoxynucleotides containing N1-methyl-2'-deoxyadenosine and N6-methyl-2'-deoxyadenosine

Chemoenzymatic synthesis of cytokinins from nucleosides: ribose as a blocking group

Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.

Oligonucleotides Containing Disaccharide Nucleosides: Synthesis, Physicochemical, and Substrate Properties

A comparative study on the cleavage of stereoisomeric uridylyl(3',5')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts.

Substrate properties of C'-methyl UTP derivatives in T7 RNA polymerase reactions. Evidence for N-type NTP conformation

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases

Incorporation of a disaccharide nucleoside into the backbone of double-stranded DNA: crystallization and preliminary X-ray diffraction

Determination of the nucleotide conformation in the productive enzyme-substrate complexes of RNA-depolymerases

Chemical incorporation of 1-methyladenosine, minor tRNA component, into oligonucleotides.

Distinct Peculiarities of In Planta Synthesis of Isoprenoid and Aromatic Cytokinins

Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine

Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine Nucleosides

Physicochemical characterization of uridine phosphorylase from Shewanella oneidensis MR-1