List of works - Benjamin M. Neale

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

scientific article published on 01 June 2020

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation

M69 EVALUATING THE AGE-OF-ONSET-DEPENDENT GENETIC ARCHITECTURE OF COMPLEX DISORDERS IN THE UK BIOBANK

scholarly article

M79 THE INTERPLAY BETWEEN SCHIZOPHRENIA AND INTELLIGENCE POLYGENIC RISK SCORES CONTRIBUTES TO COMMUNITY FUNCTIONING IN PEOPLE WITH PSYCHOTIC DISORDER

scholarly article

P3‐119: ATTENTION IS PREDICTED BY ALZHEIMER'S DISEASE POLYGENIC RISK SCORE IN TYPICALLY DEVELOPING CHILDREN MORE THAN CHILDREN WITH ATTENTION/DEFICIT‐HYPERACTIVITY DISORDER

scholarly article

Increasing Trans-Ethnic Diversity In Genome-Wide Association Meta-Analysis Of ADHD

scholarly article

EVALUATION OF THE IMPACT OF ULTRA-RARE VARIANTS IN CANNABIS USE DISORDER USING EXOME SEQUENCING

scholarly article

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

6.71 ATTENTION IS PREDICTED BY ALZHEIMER’S DISEASE POLYGENIC RISK SCORE IN TYPICALLY DEVELOPING CHILDREN MORE THAN IN CHILDREN WITH ADHD

scholarly article

Genome studies must account for history-Response

scientific article published on 01 December 2019

37 CONTRIBUTIONS OF COPY NUMBER VARIANTS TO HUMAN COMPLEX TRAITS

scholarly article

GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

scientific article published on 16 November 2020

Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases

LARGE META-ANALYSIS OF SCANDINAVIAN EXOME SEQUENCING STUDIES OF SCHIZOPHRENIA

scholarly article

45 EXOME SEQUENCING OF 25,000 SCHIZOPHRENIA CASES IMPLICATES 10 RISK GENES, AND PROVIDES INSIGHT INTO SHARED AND DISTINCT GENETIC RISK AND BIOLOGY WITH OTHER NEURODEVELOPMENTAL DISORDERS

scholarly article

Estimation of metabolic syndrome heritability in three large populations including full pedigree and genomic information

scientific article published on 01 June 2019

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Statistical Power and the Classical Twin Design

scientific article published on 01 April 2020

The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric Disorders

GWAS meta-analysis highlights the hypothalamic-pituitary-gonadal axis (HPG axis) in the genetic regulation of menstrual cycle length

Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation

IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA

scholarly article

INITIAL RESULTS FROM THE META-ANALYSIS OF THE WHOLE-EXOMES OF OVER 20,000 SCHIZOPHRENIA CASES AND 45,000 CONTROLS

scholarly article

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

preprint published 25 September 2016

153. A Novel Framework for Well-Calibrated Analysis of Complex Traits in Admixed Individuals

scholarly article

PERSPECTIVE ON DATA SHARING AND OPEN SCIENCE IN PSYCHIATRIC GENETICS

scholarly article

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

A data-driven medication score predicts 10-year mortality among aging adults

scientific article published on 25 September 2020

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG

scientific article published on 01 August 2019

Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language

scientific article published on 5 March 2018

The Role of Ultra-Rare Coding Variants In ADHD

scholarly article

EXPLORING SEX DIFFERENCES IN THE GENETICS OF UK BIOBANK PHENOTYPES

scholarly article

13. The Role of Common and Rare Variants in ADHD Risk and Genetic Overlap With Other Phenotypes

scholarly article

Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans

scientific article

List of works by Benjamin M. Neale

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation

M69 EVALUATING THE AGE-OF-ONSET-DEPENDENT GENETIC ARCHITECTURE OF COMPLEX DISORDERS IN THE UK BIOBANK

M79 THE INTERPLAY BETWEEN SCHIZOPHRENIA AND INTELLIGENCE POLYGENIC RISK SCORES CONTRIBUTES TO COMMUNITY FUNCTIONING IN PEOPLE WITH PSYCHOTIC DISORDER

P3‐119: ATTENTION IS PREDICTED BY ALZHEIMER'S DISEASE POLYGENIC RISK SCORE IN TYPICALLY DEVELOPING CHILDREN MORE THAN CHILDREN WITH ATTENTION/DEFICIT‐HYPERACTIVITY DISORDER

Increasing Trans-Ethnic Diversity In Genome-Wide Association Meta-Analysis Of ADHD

EVALUATION OF THE IMPACT OF ULTRA-RARE VARIANTS IN CANNABIS USE DISORDER USING EXOME SEQUENCING

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

Genome-wide association study identifies 48 common genetic variants associated with handedness

6.71 ATTENTION IS PREDICTED BY ALZHEIMER’S DISEASE POLYGENIC RISK SCORE IN TYPICALLY DEVELOPING CHILDREN MORE THAN IN CHILDREN WITH ADHD

Genome studies must account for history-Response

37 CONTRIBUTIONS OF COPY NUMBER VARIANTS TO HUMAN COMPLEX TRAITS

GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases

LARGE META-ANALYSIS OF SCANDINAVIAN EXOME SEQUENCING STUDIES OF SCHIZOPHRENIA

45 EXOME SEQUENCING OF 25,000 SCHIZOPHRENIA CASES IMPLICATES 10 RISK GENES, AND PROVIDES INSIGHT INTO SHARED AND DISTINCT GENETIC RISK AND BIOLOGY WITH OTHER NEURODEVELOPMENTAL DISORDERS

Estimation of metabolic syndrome heritability in three large populations including full pedigree and genomic information

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Statistical Power and the Classical Twin Design

The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric Disorders

GWAS meta-analysis highlights the hypothalamic-pituitary-gonadal axis (HPG axis) in the genetic regulation of menstrual cycle length

Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation

IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA

INITIAL RESULTS FROM THE META-ANALYSIS OF THE WHOLE-EXOMES OF OVER 20,000 SCHIZOPHRENIA CASES AND 45,000 CONTROLS

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

153. A Novel Framework for Well-Calibrated Analysis of Complex Traits in Admixed Individuals

PERSPECTIVE ON DATA SHARING AND OPEN SCIENCE IN PSYCHIATRIC GENETICS

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

A data-driven medication score predicts 10-year mortality among aging adults

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG

Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language

The Role of Ultra-Rare Coding Variants In ADHD

EXPLORING SEX DIFFERENCES IN THE GENETICS OF UK BIOBANK PHENOTYPES

13. The Role of Common and Rare Variants in ADHD Risk and Genetic Overlap With Other Phenotypes

Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans