List of works - Benjamin M. Neale

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

scientific article published on 20 May 2012

zCall: a rare variant caller for array-based genotyping: genetics and population analysis

scientific article

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

scientific article published on 9 April 2018

Clinical use of current polygenic risk scores may exacerbate health disparities

scientific article published on 29 March 2019

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

scientific article

Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples

scientific article published on 13 February 2017

The mutational constraint spectrum quantified from variation in 141,456 humans

scientific article published on 27 May 2020

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

scientific article published in October 2013

Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants

scientific article

Multi-trait analysis of genome-wide association summary statistics using MTAG.

scientific article published in January 2018

Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity Disorder

scientific article published on August 5, 2010

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

scientific article published on February 2016

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder

scientific journal article

Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

scientific article published on 11 September 2017

High loading of polygenic risk for ADHD in children with comorbid aggression

scientific article published on August 2013

The statistical properties of gene-set analysis

scientific article published on 12 April 2016

The IMAGE project: methodological issues for the molecular genetic analysis of ADHD.

scientific article

Whole-genome analyses of whole-brain data: working within an expanded search space

scientific article

The mutational constraint spectrum quantified from variation in 141,456 humans

scientific article published on 28 January 2019

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

scientific article

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

scientific article

Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder

scientific article

Common body mass index-associated variants confer risk of extreme obesity

scientific article

Genome-wide association study in German patients with attention deficit/hyperactivity disorder

scientific article published on 19 October 2011

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study

scientific journal article

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

article

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

article

Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan

scientific journal article

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder

scientific article published on December 2008

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder

scientific article published on 26 April 2018

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae

scientific article

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

scientific article published on 11 May 2016

Autism spectrum disorder severity reflects the average contribution of de novo and familial influences

scientific article

Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post-mortem midbrain tissue

scientific article published in December 2007

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders

scientific article published on 26 June 2017

Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics

scientific article published in April 2004

Phenome-wide heritability analysis of the UK Biobank

scientific article

Body dissatisfaction and drive for thinness in young adult twins

scientific article published in April 2005

A twin study of dietary restraint, disinhibition and hunger: an examination of the eating inventory (three factor eating questionnaire).

scientific article

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits

article

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study

scientific article

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

scientific article

Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder

scientific article published on 26 March 2013

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

scientific article published on 03 October 2016

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Comorbidity of tic disorders & ADHD: conceptual and methodological considerations

scientific article published on June 2007

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

scientific article published in Nature Communications

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

scientific article published on 05 August 2016

List of works by Benjamin M. Neale

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

zCall: a rare variant caller for array-based genotyping: genetics and population analysis

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

Clinical use of current polygenic risk scores may exacerbate health disparities

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples

The mutational constraint spectrum quantified from variation in 141,456 humans

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants

Multi-trait analysis of genome-wide association summary statistics using MTAG.

Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity Disorder

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder

Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

High loading of polygenic risk for ADHD in children with comorbid aggression

The statistical properties of gene-set analysis

The IMAGE project: methodological issues for the molecular genetic analysis of ADHD.

Whole-genome analyses of whole-brain data: working within an expanded search space

The mutational constraint spectrum quantified from variation in 141,456 humans

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder

Common body mass index-associated variants confer risk of extreme obesity

Genome-wide association study in German patients with attention deficit/hyperactivity disorder

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

Autism spectrum disorder severity reflects the average contribution of de novo and familial influences

Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post-mortem midbrain tissue

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders

Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics

Phenome-wide heritability analysis of the UK Biobank

Body dissatisfaction and drive for thinness in young adult twins

A twin study of dietary restraint, disinhibition and hunger: an examination of the eating inventory (three factor eating questionnaire).

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Comorbidity of tic disorders & ADHD: conceptual and methodological considerations

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts