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Authors whose works are in public domain in at least one jurisdiction

List of works by Jennifer Doudna

1-50 of 352 results

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

scientific article

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

scientific article

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

scientific article (publication date: 28 February 2013)

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

scientific article

RNA-programmed genome editing in human cells

scientific article (publication date: 29 January 2013)

RNA-guided genetic silencing systems in bacteria and archaea

scientific article (publication date: 15 February 2012)

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

scientific article published on August 11, 2013

Crystal structure of a group I ribozyme domain: principles of RNA packing

scientific article

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

scientific article

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

scientific article published on December 15, 2014

Structural basis for double-stranded RNA processing by Dicer

scientific article

Crystal structure of a hepatitis delta virus ribozyme

scientific article

Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering

scientific article published on January 14, 2016

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

scientific article

A three-dimensional view of the molecular machinery of RNA interference

scientific article

Molecular Mechanisms of RNA Interference

scientific article published on January 1, 2013

Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit

scientific article (publication date: 9 March 2001)

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

scientific article

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

scientific article

The chemical repertoire of natural ribozymes

scientific article

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

scientific article

Structures of the RNA-guided surveillance complex from a bacterial immune system

scientific article

Mechanism of ribosome recruitment by hepatitis C IRES RNA

scientific article

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

scientific article published on May 2, 2011

Adaptive strategies of the influenza virus polymerase for replication in humans

scientific article

In vitro reconstitution of the human RISC-loading complex

scientific article

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

scientific article

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

scientific article published on 20 September 2017

Programmable RNA recognition and cleavage by CRISPR/Cas9.

scientific article

Crystal structure of the ribonucleoprotein core of the signal recognition particle

scientific article

Biotechnology. A prudent path forward for genomic engineering and germline gene modification

scientific article

Applications of CRISPR technologies in research and beyond

scientific article

RNA tertiary structure mediation by adenosine platforms

scientific article

Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

scientific article

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

scientific article

Structural roles for human translation factor eIF3 in initiation of protein synthesis

scientific article

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3

scientific article

Conformational control of DNA target cleavage by CRISPR-Cas9.

scientific article published on 28 October 2015

Insights into RNA structure and function from genome-wide studies

scientific article published on May 13, 2014

Programmable RNA Tracking in Live Cells with CRISPR/Cas9.

scientific article

CRISPR-Cas9 Structures and Mechanisms

scientific article

Tertiary Motifs in RNA Structure and Folding

scientific article

The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold

scientific article published in September 1999

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

scientific article

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

scientific article

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

scientific article published on 26 September 2016

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

scientific article published on 15 February 2018

A conformational switch controls hepatitis delta virus ribozyme catalysis

scientific article

A universal mode of helix packing in RNA.

scientific article

Structural determinants of RNA recognition and cleavage by Dicer

scientific article published on 16 September 2007