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List of works by Jennifer Doudna

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

scientific article
Genome editing. The new frontier of genome engineering with CRISPR-Cas9

scientific article
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

scientific article (publication date: 28 February 2013)
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

scientific article
RNA-programmed genome editing in human cells

scientific article (publication date: 29 January 2013)
RNA-guided genetic silencing systems in bacteria and archaea

scientific article (publication date: 15 February 2012)
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

scientific article published on August 11, 2013
Crystal structure of a group I ribozyme domain: principles of RNA packing

scientific article
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

scientific article
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

scientific article published on December 15, 2014
Structural basis for double-stranded RNA processing by Dicer

scientific article
Crystal structure of a hepatitis delta virus ribozyme

scientific article
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering

scientific article published on January 14, 2016
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

scientific article
A three-dimensional view of the molecular machinery of RNA interference

scientific article
Molecular Mechanisms of RNA Interference

scientific article published on January 1, 2013
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit

scientific article (publication date: 9 March 2001)
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

scientific article
Structural basis for CRISPR RNA-guided DNA recognition by Cascade

scientific article
The chemical repertoire of natural ribozymes

scientific article
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

scientific article
Structures of the RNA-guided surveillance complex from a bacterial immune system

scientific article
Mechanism of ribosome recruitment by hepatitis C IRES RNA

scientific article
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

scientific article published on May 2, 2011
Adaptive strategies of the influenza virus polymerase for replication in humans

scientific article
In vitro reconstitution of the human RISC-loading complex

scientific article
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

scientific article
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

scientific article published on 20 September 2017
Programmable RNA recognition and cleavage by CRISPR/Cas9.

scientific article
Crystal structure of the ribonucleoprotein core of the signal recognition particle

scientific article
Biotechnology. A prudent path forward for genomic engineering and germline gene modification

scientific article
Applications of CRISPR technologies in research and beyond

scientific article
RNA tertiary structure mediation by adenosine platforms

scientific article
Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

scientific article
Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

scientific article
Structural roles for human translation factor eIF3 in initiation of protein synthesis

scientific article
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3

scientific article
Conformational control of DNA target cleavage by CRISPR-Cas9.

scientific article published on 28 October 2015
Insights into RNA structure and function from genome-wide studies

scientific article published on May 13, 2014
Programmable RNA Tracking in Live Cells with CRISPR/Cas9.

scientific article
CRISPR-Cas9 Structures and Mechanisms

scientific article
Tertiary Motifs in RNA Structure and Folding

scientific article
The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold

scientific article published in September 1999
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

scientific article
STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

scientific article
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

scientific article published on 26 September 2016
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

scientific article published on 15 February 2018
A conformational switch controls hepatitis delta virus ribozyme catalysis

scientific article
A universal mode of helix packing in RNA.

scientific article
Structural determinants of RNA recognition and cleavage by Dicer

scientific article published on 16 September 2007

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