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List of works by Vítězslav Bryja

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Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

scientific article published on 9 January 2008
Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord.

scientific article
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism

scientific journal article
Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer.

scientific article published on 31 March 2015
Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation

scientific article
Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.

scientific article
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.

scholarly article
Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion

scientific journal article
Derivation of mouse embryonic stem cells

scientific article published on 01 January 2006
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo

scientific journal article
Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

scientific article
Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.

scientific article
An efficient method for the derivation of mouse embryonic stem cells.

scientific article published on 9 December 2005
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2to LRP6 phosphorylation

scientific article published on February 8, 2011
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex

scientific article
Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha.

scientific article published on 18 December 2008
Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway

scientific article published on 18 March 2014
Wnt2 regulates progenitor proliferation in the developing ventral midbrain

scientific journal article
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

scientific journal article
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways

scientific article published on 24 October 2008
Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

scientific article published on 9 March 2010
Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells.

scientific article
Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

scientific article
SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells

scientific journal article
High molecular weight FGF2: the biology of a nuclear growth factor.

scientific article published on January 2009
FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

scientific article published on March 31, 2010
Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6.

scientific article published on 5 February 2014
NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells

scientific article
Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

scientific article published on 02 August 2016
Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation.

scientific article published in May 2007
Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage.

scientific article
Genetic interaction between Lrp6 and Wnt5a during mouse development

scientific journal article
Aryl hydrocarbon receptor-activating polychlorinated biphenyls and their hydroxylated metabolites induce cell proliferation in contact-inhibited rat liver epithelial cells.

scientific article
Post-translational modifications regulate signalling by Ror1.

scientific article published on 27 May 2011
Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia

scientific article
Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands

scientific article
WNT unrelated activities in commercially available preparations of recombinant WNT3a.

scientific article
Increased apoptosis in differentiating p27-deficient mouse embryonic stem cells.

scientific article published in June 2004
Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes

scientific article published on 12 October 2008
beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?

scientific article
Abnormal development of mouse embryoid bodies lacking p27Kip1 cell cycle regulator

scientific article published on 07 June 2005
Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.

scientific article published on 6 July 2015
WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins.

scientific article published on 8 November 2010
N-terminal part of Dishevelled DEP domain is required for Wnt/β-catenin signaling in mammalian cells

scientific article published on 3 July 2017
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner.

scientific article
The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?

scientific article published on 25 July 2017
A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway

scientific article
Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.

scientific article
Casein Kinase 1 is a Therapeutic Target in Chronic Lymphocytic Leukemia.

scientific article published on 9 January 2018
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation

scientific article

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