List of works - Joanna Wietrzyk

Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.

scientific article published on 25 November 2014

The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration.

scientific article

Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation.

scientific article published on 22 May 2018

Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment.

scientific article published on January 2014

Novel genistein derivatives induce cell death and cell cycle arrest through different mechanisms

scientific article published on January 2013

Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines.

scientific article

Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models

scientific article published on 5 December 2017

Influence of the structure of new anthracycline antibiotics on their biological properties.

scientific article published on May 2005

Synthesis and in vitro antiproliferative activity of thiazole-based nitrogen mustards: the hydrogen bonding interaction between model systems and nucleobases

scientific article

Biological activity of doubly modified salinomycin analogs - Evaluation in vitro and ex vivo

scientific article published on 10 July 2018

The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: highly selective cytotoxic agents

scientific article published on 20 October 2015

Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents

scientific article

Simple phosphonic inhibitors of human neutrophil elastase.

scientific article published on 22 January 2011

Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines.

scientific article published on 19 March 2014

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids

scientific article published on 09 November 2018

Antitumor properties of (5E,7E) analogs of vitamin D3.

scientific article published on 12 March 2010

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.

scientific article

Structural factors affecting cytotoxic activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one derivatives.

scientific article published on 28 February 2014

Design, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents.

scientific article published on 18 November 2014

Antitumour and antimetastatic effect of genistein alone or combined with cyclophosphamide in mice transplanted with various tumours depends on the route of tumour transplantation

scientific article published on 01 March 2000

Vitamin D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model.

scientific article published on 15 December 2017

The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells

scientific article published in January 2012

Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

scientific article published on 08 September 2011

Antiangiogenic and antitumour effects in vivo of genistein applied alone or combined with cyclophosphamide.

scientific article published in November 2001

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles.

scientific article

Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812.

scientific article published on 26 April 2018

Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging.

scientific article published on 19 September 2017

Silver(I) complexes with hydantoins and allantoin: synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics

scientific article

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines.

scientific article

Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

scientific article published on January 2004

siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells

scientific article published on 10 August 2012

Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice

scientific article published on 01 January 1998

Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5-a]pyrimidine derivatives: Structural characterization and mechanism of the suppression of tumor cell growth

scientific article published on August 19, 2014

Synthesis and biological properties of oxazolinodaunorubicin--a new derivative of daunorubicin with a modified daunosamine moiety.

scientific article published on 28 August 2009

Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies

scientific article

Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors.

scientific article

The Toxicokinetic Profile of Dex40-GTMAC3-a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin

scientific article published on 17 March 2016

Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection

scientific article published on 04 October 2018

Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling.

scientific article published on 12 February 2017

Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents

scientific article published on 19 November 2018

Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice

scientific article published on 5 July 2016

The antitumor effect of postoperative treatment with genistein alone or combined with cyclophosphamide in mice bearing transplantable tumors

scientific article published on 01 November 2000

Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives

scientific article published on February 2004

Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents.

scientific article published on 18 May 2012

Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

scientific article published on 12 September 2018

Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine.

scientific article published on 23 May 2012

One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic--lasalocid acid.

scientific article published on 26 July 2013

New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

scientific article

Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents

scientific article published on 08 October 2019

Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole).

scientific article published in January 2001

List of works by Joanna Wietrzyk

Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.

The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration.

Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation.

Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment.

Novel genistein derivatives induce cell death and cell cycle arrest through different mechanisms

Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines.

Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models

Influence of the structure of new anthracycline antibiotics on their biological properties.

Synthesis and in vitro antiproliferative activity of thiazole-based nitrogen mustards: the hydrogen bonding interaction between model systems and nucleobases

Biological activity of doubly modified salinomycin analogs - Evaluation in vitro and ex vivo

The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: highly selective cytotoxic agents

Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents

Simple phosphonic inhibitors of human neutrophil elastase.

Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines.

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids

Antitumor properties of (5E,7E) analogs of vitamin D3.

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.

Structural factors affecting cytotoxic activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one derivatives.

Design, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents.

Antitumour and antimetastatic effect of genistein alone or combined with cyclophosphamide in mice transplanted with various tumours depends on the route of tumour transplantation

Vitamin D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model.

The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells

Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

Antiangiogenic and antitumour effects in vivo of genistein applied alone or combined with cyclophosphamide.

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles.

Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812.

Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging.

Silver(I) complexes with hydantoins and allantoin: synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines.

Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells

Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice

Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5-a]pyrimidine derivatives: Structural characterization and mechanism of the suppression of tumor cell growth

Synthesis and biological properties of oxazolinodaunorubicin--a new derivative of daunorubicin with a modified daunosamine moiety.

Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies

Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors.

The Toxicokinetic Profile of Dex40-GTMAC3-a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin

Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection

Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling.

Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents

Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice

The antitumor effect of postoperative treatment with genistein alone or combined with cyclophosphamide in mice bearing transplantable tumors

Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives

Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents.

Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine.

One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic--lasalocid acid.

New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents

Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole).