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List of works by Lorraine M Work

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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

scientific article
A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury

scientific article
Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses

scientific article published on 4 January 2006
Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism

scientific article published in July 2006
Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia

scholarly article
Development of efficient viral vectors selective for vascular smooth muscle cells

scientific article published in February 2004
Oxidative Stress and the Use of Antioxidants in Stroke

scientific article
Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop

scientific article published on 23 January 2007
Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor

scientific journal article
Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo

scientific article
Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions.

scientific article published on 15 November 2007
Differential expression of microRNA-206 and its target genes in preeclampsia

scientific article
Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p.

scientific article published on 5 June 2007
NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs

scientific article (publication date: April 2002)
Cell-selective viral gene delivery vectors for the vasculature

scientific article
Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature

scientific article
Use of phage display to identify novel peptides for targeted gene therapy

scientific article published on January 2002
Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats.

scientific article
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

scientific article
Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats

scientific article published on 3 March 2008
Dual targeting of gene delivery by genetic modification of adenovirus serotype 5 fibers and cell-selective transcriptional control.

scientific article published on August 2004
Gene Therapy for Cardiovascular Disease

scientific article published on January 1, 2003
Vascular-targeting antioxidant therapy in a model of hypertension and stroke

article
Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector

scientific article
Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats

scientific article published on 11 September 2012
Altered Extracellular Vesicle MicroRNA Expression in Ischemic Stroke and Small Vessel Disease

scientific article published on 07 January 2019
Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment - a review of contemporary studies

scientific article published on 11 September 2018
Preclinical Validation of the Therapeutic Potential of Glasgow Oxygen Level Dependent (GOLD) Technology: a Theranostic for Acute Stroke

scientific article published on 30 November 2018
Targeting gene therapy vectors to the vascular endothelium

scientific article
In vivo biopanning: A methodological approach to identifying novel targeting ligands for delivery of biological agents to the vasculature.

scientific article
UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings

scientific article published on 09 March 2020
Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion

scientific article published on 28 February 2019

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