List of works - Mark L. Evans

Does insulin lispro preserve the physiological defences to hypoglycaemia during intensive insulin therapy with a conventional basal bolus regimen?

scientific article

Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention.

scientific article published on March 2014

A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial

scientific article published in April 2017

Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes

scientific article published on February 2015

Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.

scientific article published in May 2004

Recurrent hypoglycemia increases hypothalamic glucose phosphorylation activity in rats

scientific article

Distribution of cells responsive to 5-HT₆ receptor antagonist-induced hypophagia

scientific article published on 21 February 2014

Assessing the effectiveness of a 3-month day-and-night home closed-loop control combined with pump suspend feature compared with sensor-augmented pump therapy in youths and adults with suboptimally controlled type 1 diabetes: a randomised parallel s

scientific article

Brain glucosamine boosts protective glucoprivic feeding

scientific article

Acute Ingestion of Caffeinated Chewing Gum Improves Repeated Sprint Performance of Team Sports Athletes With Low Habitual Caffeine Consumption

scientific article

Recurrent hypoglycemia is associated with loss of activation in rat brain cingulate cortex

scientific article published on 6 March 2012

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial

scientific article published on 01 June 2019

Hypothalamic glucose sensing and glycaemic disease

scientific article published on March 2011

Hypoglycaemia and glucose sensing

scientific article published in October 1997

Low-Blood Glucose Avoidance Training Improves Glycemic Variability in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: HypoCOMPaSS Trial

scientific article published on 7 March 2016

The use of a portable breath analysis device in monitoring type 1 diabetes patients in a hypoglycaemic clamp: validation with SIFT-MS data.

scientific article

The action profile of lispro is not blunted by mixing in the syringe with NPH insulin

scientific article published on 01 December 1998

Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial)

scientific article

Glucose Turnover After Replacement of Usual Therapy by Insulin in Insulin-naive Type 2 Diabetes Subjects

scientific article published on February 25, 2014

Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes

scientific article published on 7 April 2015

BAD modulates counterregulatory responses to hypoglycemia and protective glucoprivic feeding

scientific article

Nutritional state influences Nociceptin/Orphanin FQ peptide receptor expression in the dorsal raphe nucleus

scientific article published on 16 September 2009

Behavioral Patterns and Associations with Glucose Control During 12-Week Randomized Free-Living Clinical Trial of Day and Night Hybrid Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes

scientific article published on 2 May 2017

Exhaled Breath Isoprene Rises During Hypoglycemia in Type 1 Diabetes

scientific article published in July 2016

Comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

scientific article published in October 2014

Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations

scientific article

Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme

scientific article published on 26 January 2011

A randomized, multicentre trial evaluating the efficacy and safety of fast-acting insulin aspart in continuous subcutaneous insulin infusion in adults with type 1 diabetes (onset 5)

scientific article published on 13 January 2019

Use of fast-acting insulin aspart in insulin pump therapy in clinical practice

scientific article published on 19 June 2019

Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats

scientific article published on 14 October 2016

Rapid Benefits of Structured Optimization and Sensor-Augmented Insulin Pump Therapy in Adults With Type 1 Diabetes

scientific article published on 21 June 2016

Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes

scientific article published on 7 October 2015

Too Much or Too Little? The Double Jeopardy of Subcutaneous Insulin Therapy in Diabetes

scientific article published on 01 October 2015

Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion

scientific article published on 01 December 2011

Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes.

scientific article

Avoiding hypoglycaemia when treating type 1 diabetes

scientific article

A new integrated care pathway for ambulance attended severe hypoglycaemia in the East of England: The Eastern Academic Health Science Network (EAHSN) model

scientific article published in September 2017

Association between recent exposure to continuous glucose monitoring‐recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes

Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventiona

scientific article published in December 2014

Keto diets: good, bad or ugly?

scientific article published on 31 August 2018

Hypoglycaemia. Avoid 50% dextrose

scientific article published on 08 March 2011

Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study

Bolusing frequency and amount impacts glucose control during hybrid closed-loop

scientific article published on 29 July 2017

Evaluating the Performance of a Novel Embedded Closed-loop System

scientific article published on 24 March 2014

Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)

Predicting risk of severe hypoglycaemia in type 2 diabetes

scientific article published on 21 March 2015

List of works by Mark L. Evans

Does insulin lispro preserve the physiological defences to hypoglycaemia during intensive insulin therapy with a conventional basal bolus regimen?

Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention.

A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial

Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes

Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.

Recurrent hypoglycemia increases hypothalamic glucose phosphorylation activity in rats

Distribution of cells responsive to 5-HT₆ receptor antagonist-induced hypophagia

Assessing the effectiveness of a 3-month day-and-night home closed-loop control combined with pump suspend feature compared with sensor-augmented pump therapy in youths and adults with suboptimally controlled type 1 diabetes: a randomised parallel s

Brain glucosamine boosts protective glucoprivic feeding

Acute Ingestion of Caffeinated Chewing Gum Improves Repeated Sprint Performance of Team Sports Athletes With Low Habitual Caffeine Consumption

Recurrent hypoglycemia is associated with loss of activation in rat brain cingulate cortex

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial

Hypothalamic glucose sensing and glycaemic disease

Hypoglycaemia and glucose sensing

Low-Blood Glucose Avoidance Training Improves Glycemic Variability in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: HypoCOMPaSS Trial

The use of a portable breath analysis device in monitoring type 1 diabetes patients in a hypoglycaemic clamp: validation with SIFT-MS data.

The action profile of lispro is not blunted by mixing in the syringe with NPH insulin

Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial)

Glucose Turnover After Replacement of Usual Therapy by Insulin in Insulin-naive Type 2 Diabetes Subjects

Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes

BAD modulates counterregulatory responses to hypoglycemia and protective glucoprivic feeding

Nutritional state influences Nociceptin/Orphanin FQ peptide receptor expression in the dorsal raphe nucleus

Behavioral Patterns and Associations with Glucose Control During 12-Week Randomized Free-Living Clinical Trial of Day and Night Hybrid Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes

Exhaled Breath Isoprene Rises During Hypoglycemia in Type 1 Diabetes

Comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations

Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme

A randomized, multicentre trial evaluating the efficacy and safety of fast-acting insulin aspart in continuous subcutaneous insulin infusion in adults with type 1 diabetes (onset 5)

Use of fast-acting insulin aspart in insulin pump therapy in clinical practice

Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats

Rapid Benefits of Structured Optimization and Sensor-Augmented Insulin Pump Therapy in Adults With Type 1 Diabetes

Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes

Too Much or Too Little? The Double Jeopardy of Subcutaneous Insulin Therapy in Diabetes

Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion

Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes.

Avoiding hypoglycaemia when treating type 1 diabetes

A new integrated care pathway for ambulance attended severe hypoglycaemia in the East of England: The Eastern Academic Health Science Network (EAHSN) model

Association between recent exposure to continuous glucose monitoring‐recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes

Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventiona

Keto diets: good, bad or ugly?

Hypoglycaemia. Avoid 50% dextrose

Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study

Bolusing frequency and amount impacts glucose control during hybrid closed-loop

Evaluating the Performance of a Novel Embedded Closed-loop System

Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)

Predicting risk of severe hypoglycaemia in type 2 diabetes