List of works - Nathaniel J. Szewczyk

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

scientific article

Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction.

scientific article published in October 2006

Chemically defined medium and Caenorhabditis elegans

scientific article

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling

scientific article published on 13 July 2015

A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

scientific article published on 31 December 2013

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

scientific article (publication date: 2012)

Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight

scientific article published on August 2006

An overview of technical considerations for Western blotting applications to physiological research.

scientific article

Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

scientific article published on 22 September 2016

Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans

scientific article

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

scientific article published on 3 July 2013

Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway

scientific article published on May 21, 2013

Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans

scientific article

Genomic response of the nematode Caenorhabditis elegans to spaceflight

scientific article published on January 2008

Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans

scientific article published on 01 June 2000

Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans

scientific article published on 8 February 2007

Transgene-coded chimeric proteins as reporters of intracellular proteolysis: Starvation-induced catabolism of alacZ fusion protein in muscle cells ofCaenorhabditis elegans

scientific article published on October 1, 1997

Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia

scientific article

The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans

scientific article (publication date: December 2010)

Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans

scientific article

Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants

scientific article

unc-94 encodes a tropomodulin in Caenorhabditis elegans

scientific article

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

scientific article published on 06 January 2014

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

scientific article

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans

scientific article

Signal-transduction networks and the regulation of muscle protein degradation.

scientific article

Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans

scientific article published on 21 January 2016

Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males

scientific article published on 2 August 2017

Knockdown of the C. elegans Kinome identifies Kinases required for normal protein Homeostasis, Mitochondrial network structure, and Sarcomere structure in muscle

scientific article published on September 23, 2013

Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

scientific article

Methods to assess subcellular compartments of muscle in C. elegans

scientific article

Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of and its functional response to drugs

article

The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight

scientific article (publication date: 2011)

Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station.

scientific article

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism.

scientific article published on 6 October 2017

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal muscle

scientific article published on 15 August 2017

NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans

scientific article published on 01 July 2018

Remote automated multi-generational growth and observation of an animal in low Earth orbit

scientific article published on November 30, 2011

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.

scientific article

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.

scientific article published on 2 November 2012

Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).

scientific article published on September 2007

C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO.

scientific article

Spaceflight and ageing: reflecting on Caenorhabditis elegans in space

scientific article published on 5 November 2013

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae

scientific article published on 22 August 2019

Surviving atmospheric spacecraft breakup.

scientific article published on January 2005

Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle

scientific article published on 15 May 2017

Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling

scientific article published on 7 April 2016

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in

scientific article published on 01 November 2018

The acute transcriptional response to resistance exercise: impact of age and contraction mode

Don't 'agonise' over the mechanisms underlying beta-agonist-induced muscle hypertrophy!

scientific article published on 01 January 2011

List of works by Nathaniel J. Szewczyk

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction.

Chemically defined medium and Caenorhabditis elegans

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling

A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight

An overview of technical considerations for Western blotting applications to physiological research.

Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway

Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans

Genomic response of the nematode Caenorhabditis elegans to spaceflight

Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans

Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans

Transgene-coded chimeric proteins as reporters of intracellular proteolysis: Starvation-induced catabolism of alacZ fusion protein in muscle cells ofCaenorhabditis elegans

Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia

The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans

Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans

Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants

unc-94 encodes a tropomodulin in Caenorhabditis elegans

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans

Signal-transduction networks and the regulation of muscle protein degradation.

Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans

Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males

Knockdown of the C. elegans Kinome identifies Kinases required for normal protein Homeostasis, Mitochondrial network structure, and Sarcomere structure in muscle

Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

Methods to assess subcellular compartments of muscle in C. elegans

Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of and its functional response to drugs

The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight

Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station.

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism.

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal muscle

NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans

Remote automated multi-generational growth and observation of an animal in low Earth orbit

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.

Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).

C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO.

Spaceflight and ageing: reflecting on Caenorhabditis elegans in space

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae

Surviving atmospheric spacecraft breakup.

Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle

Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in

The acute transcriptional response to resistance exercise: impact of age and contraction mode

Don't 'agonise' over the mechanisms underlying beta-agonist-induced muscle hypertrophy!